The initial events after photoexcitation and photoionization of α-tocopherol (vitamin E) and the analogue Trolox C have been studied by femtosecond stimulated Raman spectroscopy, transient absorption spectroscopy and time-resolved infrared spectroscopy. Using these techniques it was possible to follow the formation and decay of the excited state, neutral and radical cation radicals and the hydr...

We consider the Rosenfeld-Gröbner algorithm for computing a regular decomposition of a radical differential ideal generated by a set of ordinary differential polynomials in n indeterminates. For a set of ordinary differential polynomials F , let M(F ) be the sum of maximal orders of differential indeterminates occurring in F . We propose a modification of the Rosenfeld-Gröbner algorithm, in whi...

The light-induced electron transfer reaction of flavin cofactor photoactivation in Xenopus laevis (6-4) photolyase has been studied by continuous-wave and time-resolved electron paramagnetic resonance spectroscopy. When the photoactivation is initiated from the fully oxidized form of the flavin, a neutral flavin radical is observed as a long-lived paramagnetic intermediate of two consecutive si...

OBJECTIVE The aim of this retrospective study is to evaluate the efficacy of adjuvant chemotherapy following radical hysterectomy for intermediate risk stage IB cervical cancer. METHODS From January 1993 to December 2007, a total of 100 patients of stage IB were enrolled in this study who had at least two of the following three intermediate risk factors (deep stromal invasion, lymphovascular ...

The atom-radical reaction of ground state carbon atoms (C(P)) with the vinyl radical (C2H3(X A0)) was conducted under single collision conditions at a collision energy of 32.3 2.9 kJ mol . The reaction dynamics were found to involve a complex forming reaction mechanism, which is initiated by the barrier-less addition of atomic carbon to the carbon–carbon-double bond of the vinyl radical forming...

The ability of tirapazamine (1, 3-amino-1,2,4-benzotriazine 1, 4-dioxide, SR4233) to fix DNA radical lesions is demonstrated by studying the reaction between the antitumor drug and an oligonucleotide radical that is independently produced at a defined site within a biopolymer. Using beta-mercaptoethanol as a competitor, it was determined that tirapazamine traps a C1'-nucleotide radical with a r...

We study the reaction of atomic hydrogen with formic acid and characterize the radical products using IR spectroscopy in a Kr matrix and quantum chemical calculations. The reaction first leads to the formation of an intermediate radical trans-H2COOH, which converts to the more stable radical trans-cis-HC(OH)2via hydrogen atom tunneling on a timescale of hours at 4.3 K. These open-shell species ...