Degeneration of the myelin sheath in areas of the central nervous system is a characteristic feature of multiple sclerosis (Adams, 1977; Davison, 1978). The processes that cause this degradation of myelin during the course of the disease are not yet fully defined though the involvement of invading inflammatory cells is likely (Wisniewski, 1977). Any discussion on how the myelin sheath is attack...

The effect of acetone denucleation on PTFE (Teflon) graft material was explored by measuring internodal distance in microstructure and by measuring the affinity of the graft to whole blood. Average internodal distance of untreated samples was measured to be 81 ± 19 microns compared to 28 ± 6 microns for acetone-treated samples. Average time for blood to travel through untreated samples (aided b...

Mutations inDRP2 (OMIM #300052) encoding dystrophin-related protein 2, a 957 amino acid protein, were identified in a single patient with X-linked Charcot-Marie-Tooth (CMT) disease and are associated with familial autism. DRP2 is predominantly expressed in the brain and spinal cord and functionally interacts with periaxin (PRX, OMIM #605725), a known causative CMT gene (OMIM #614895 and #145900...

We used an electron microscopic cytochemical method to determine the localization of Ca2+-ATPase in rat peripheral nerve. We found that reaction product occurred along most cytoplasmic membranes in the dorsal root ganglia (DRG). Unmyelinated axons demonstrated reaction product on the axolemma diffusely along their length. Myelinated fibers, in contrast, had reaction product limited to the axole...

Multi-carbon nanotubes (MWCNTs) having the average particle size of 71.81 nm with different concentration MWCNTs (3 and 7 g/L) graphene oxide a diameter 65.99 concentrations (20 40 mg/L), hydrogen rich water (500 ppb 1000 ppb) three sodium hydrosulfide (0.5 mg, 5 50 mg) as foliar spry along absolute control (Deionized water) were used spray at 15 days interval during 60 growth period in jasmine...

the application of conductive coatings on ferritic stainless steel can decrease electrical conductivity. theaim of this research was to investigate the electrical conductivity of cobalt coated aisi 430 ferritic stainlesssteel by pack cementation technique. coated coupons were analyzed using scanning electron microscopy(sem). electrical conductivity of the coated substrates was measured as a fun...

Fast and energy-efficient (saltatory) signal propagation along neuronal axons is made possible by the restriction of action potentials to short, specialized axonal segments, termed the nodes of Ranvier. The extended internodal segments are spared from the comparatively slow and energycostly process of membrane depolarization because they are electrically insulated with a sleeve of a multi-layer...

When an internodal cell of Chara corallina was stimulated with a mechanical pulse of various amplitudes lasting for 0.1 s (mechanical stimulus), the cell generated a receptor potential, which was highly dependent not only on the strength of the stimulus but also on the extracellular Cl- concentration. Extracellular Ca2+ was indispensable for generating receptor potential, since removal of Ca2+ ...

Antiserum to the catalytic subunit of goldfish brain (Na+, K+)-ATPase has been employed at the electron microscopic level by means of the peroxidase-antiperoxidase immunohistochemical method. In optic nerve, antigenic sites are restricted to the nodes of Ranvier. No reaction product is detected in underlying internodal neurolemma. Outgrowing neurites for cultured retinal explants devoid of glia...