We have developed a biodegradable temporizing matrix (BTM) capable of supporting secondary split-skin graft-take in animal studies. We report its first long-term implantation and use as a dermal scaffold in humans. This preliminary study assesses its ability to integrate, its ease of delamination, its ability to sustain split-skin graft in complex wounds, the degree of wound contraction, and ul...

INTRODUCTION Glycerol preserved acellular dermis (Glyaderm(®)) consists of collagen and elastin fibers and is the first non-profit dermal substitute derived from glycerol-preserved, human allogeneic skin. It is indicated for bi-layered skin reconstruction of full thickness wounds. METHODS A protocol for clinical application and optimal interval before autografting with split thickness skin gr...

INTRODUCTION Bioresorbable polymers are often used in medical procedures. Since they are biocompatible, this class of materials is a viable alternative for cases in which tissue regeneration is strongly compromised. Bioresorbable synthetic polymers may be used as membranes to support and guide cell growth through the process of tissue repair. OBJECTIVE To assess the efficiency of a porous bio...

A 14 year old boy suffering from marked penoscrotal lymphedema is reported. Reduction scrotoplasty was done and the neoscrotum was made by combining the anterior suprapubic and posterior scrotal V-shaped flaps. A split-thickness skin graft from the thigh was placed over the denuded penis. No complication was encountered and the cosmetic result was satisfactory

Radial forearm free flap surgery is a versatile technique that is widely adopted for microvascular reconstruction of the oral, oropharyngeal and hypopharyngeal lining. Nowadays, the technique for harvesting is standardized, while reconstruction of the forearm donor site defect is somewhat controversial. The authors describe a modified closure technique developed to reduce skin tension that prov...

BACKGROUND The depth of graft harvest and the residual dermis available for reepithelization primarily influence the healing of split-skin graft donor sites. When the thigh region is chosen, the authors hypothesize based on thickness measurements that the anterolateral region is the optimal donor site. METHODS Full-thickness skin specimens were sampled from the anteromedial, anterior, and ant...

Background: High-intensity interval training is a new training method that has been less explored in patients. Aim: The purpose of this study was to compare the effect of eight weeks of interval training with continuous training on changes in HRR and lipid profile in cardiac patients post-coronary artery bypass graft. Methods: In this clinical study, 30 cardiac patients of Tehran Heart Center...

Over the last decade, lymph node flap (LNF) transfer has turned out to be an effective method in the management of lymphoedema of extremities. Most of the time, the pockets created for LNF cannot be closed primarily and need to be resurfaced with split thickness skin grafts. Partial graft loss was frequently noted in these cases. The need to prevent graft loss on these iatrogenic wounds made us...

BACKGROUND In reconstructive surgery, the ultimate goal in rebuilding a structure is to provide the most similar substitute from both the functional and structural points of view. At the same time, the reconstructive surgeon should focus on minimizing donor area complications. METHODS In this report, we present our experiences with the reconstruction of distal extremity defects using a free t...

After surgical excision of hidradenitis suppurativa, reconstruction with a skin graft or a flap is performed when primary closure is not possible. However, the recurrence rate is reportedly high even after wide surgical excision. It is still unclear which reconstruction method provides the lowest recurrence rate. In this report, we present a case of intractable hidradenitis suppurativa in the b...