The impermeability of the blood-aqueous barrier to certain antibiotics precludes their use in intraocular infections, and it is very difficult to identify the causative organism if laboratory facilities are not available. With these limitations in view we embarked upon a blanket trial of framycetin sulphate (Soframycin eye drops o 5 per cent.) by intracameral injection in nine cases of intracta...

BACKGROUND To report a surgical method for treating corneal oedema in a case of late-onset Descemet membrane detachment after penetrating keratoplasty. CASE PRESENTATION A 55-year old patient presented with sudden visual loss in his left eye 28 years after penetrating keratoplasty for keratoconus. Slit-lamp biomicroscopy revealed a distortion of the corneal graft anatomy with protrusion of th...

Acute-onset postoperative endophthalmitis is a rare but vision-threatening complication of cataract surgery. The incidence rate varies substantially in the literature but is generally reported in the range of 0.03% to 0.2%. In the current issue of Ophthalmology, Creuzot-Garcher et al report a retrospective series of 6 371 242 phacoemulsification surgeries in which the rate of endophthalmitis de...

PURPOSE To investigate recent evidence in prophylaxis and management of post-cataract surgery endophthalmitis. METHODS We conducted a literature search using Pubmed database for post cataract surgery endophthalmitis, and relevant articles were selected from original English papers published since 2015. RESULTS Forty-nine articles were published regarding post-cataract surgery endophthalmiti...

To evaluate the presence of free radicals in various drugs used in ophthalmology. Twenty five samples of drugs that are used by intracameral or intravitreal route, eleven samples of drugs used as fortified eye drop, thirty samples of topical commercial preparations that are used as long term, and eight samples of autologous serum were analyzed for total free radical presence using a kit for tot...

PURPOSE To report 2 unusual cases of fungal keratitis due to Fonsecaea pedrosoi. METHODS Two patients were diagnosed with Fonsecaea pedrosoi keratitis. Their files were reviewed for predisposing factors, clinical characteristics, microbiological study, treatment, and outcome. RESULTS Two consecutive patients presented with brownish pigmented corneal ulcers in their eyes after sustaining eye...

Background: Fungal keratitis is often difficult to eradicate and requires long treatment. Antifungal agents have lower efficacy because of low tissue penetration the indolent nature infection. Fluconazole has effective ocular ability, reaching aqueous concentration as same plasm concentration. Multilayer amniotic membrane transplantation (MLAMT) been shown be a promising surgical procedure reco...