A polarographic catalytic hydrogen wave of bovine serum albumin (BSA) at about –1.80 V (vs. SCE) in NH4Cl-NH3 H2O buffer is further catalyzed by such oxidants as iodate, persulfate and hydrogen peroxide, producing a kinetic wave. Studies show that the kinetic wave is a parallel catalytic wave of hydrogen, which resulted from that hydrogen ion is electrochemically reduced and chemically regenera...

I . A survey of the incidence of goitre in Ceylon was carried out in the years 19479 and goitre was found to be endemic in the south-west sector of the Wet Zone of Ceylon. 2. In response to a request by the Ceylon Government to the World Health Organization for advice, Dr Dagmar Wilson in 1950 confirmed our earlier findings and as a short-term policy recommended the provision of iodine as KI ta...

We observed the effects of intraocular pressure (IOP), vitreous pressure and gravity on the resorption of small retinal detachments (blebs) made with Hanks' solution or autologous serum. Raising the IOP decreased the absorption time moderately and lowering the IOP increased it. These effects were greater when the RPE had been damaged by sodium iodate or laser burns, but we conclude that IOP mak...

THE increasing interest of biochemists in sulphydryl compounds has led to the necessity of finding some method for the accurate determination of these substances. That the problem is complex may be judged from the number of papers proposing new methods or modifications of old ones. The original procedure of Rosenheim and Davidsohn [1904] for the volumetric estimation of thiol acids by the use o...

PURPOSE Excessive and continuously produced free radicals in the outer retina are implicated in retinal aging and the pathogenesis of sight-threatening retinopathies, yet measuring outer retinal oxidative stress in vivo remains a challenge. Here, we test the hypothesis that continuously produced paramagnetic free radicals from the outer retina can be measured in vivo using high-resolution (22-μ...

Ultrastructural cytochemistry was used to analyze the polarized distribution of alkaline phosphatase (AP) on the plasma membranes of normal and regenerating retinal pigment epithelium (RPE) and the ciliary body epithelium in rabbits. The AP activity was concentrated on the basolateral plasma membrane in normal RPE. In regenerating RPE (after intravenous administration of sodium iodate to damage...

129I is a major by-product of nuclear fission that is of concern because of its extremely long half-life (~16 million yrs), perceived toxicity through bioaccumulation, and the increasing inventory of this radionuclide worldwide. Relatively high concentrations of iodate (27.3%) and organoiodine (23.9%) are present in a 129I-conatminated aquifer at the Savannah River Site (SRS), SC, U.S.A. To det...

BACKGROUND Hotien county in Xinjiang province, China, is an area of severe iodine deficiency and has a high infantmortality rate. We investigated whether iodine replacement through iodination of the irrigation water would decrease infant mortality. METHODS We added potassium iodate to irrigation water over a 2 to 4 week period beginning in 1992 in certain areas of three townships (Tusala, Lon...

One titrimetric and two spectrophotometric methods are proposed for the determination of diethylcarbamazine citrate (DEC) in bulk drug and in formulations using potassium iodate and potassium iodide as reagent. The methods employ the well-known analytical reaction between iodate and iodide in the presence of acid. In titrimetry (method A), the drug was treated with a measured excess of thiosulf...

The investigation of renal function in health or disease demands a reliable method for the estimation of diodone in blood and urine. The methods of Alpert (1941), Flox, Pitesky & Alving (1942), Corcoran & Page (1943) all involve the use of bromine to split iodine from the diodone molecule and to convert this into iodate. Having had a fairly wide experience in the use of diodone in the estimatio...