PURPOSE High atomic number (Z) materials have been considered as a method for enhancing radiation dose in tumors. The dose enhancement due to interactions of kilovoltage x-rays with high-Z materials (i.e., gold or iodine) has been well demonstrated through computational works. This study is to experimentally quantify the effect using gold nanoparticles (AuNPs) and iodine solutions, respectively...

this is a retrospective study on clinical course and treatment response of patients with thyroid hot nodule, referred to nuclear medicine department of shariati hospital from 1360 to 1377. from the total 58 patients with average age of 43 yr and incidence peak of 40 yr, 81% were female and 19% were male. 64% of the patients were thyrotoxic and 36% were euthyroid at presentation. thyrotoxic symp...

High-risk and refractory neuroblastomas carry poor overall survival, novel approaches must be explored to improve global outcome. With better knowledge of underlying molecular patterns growing radioligand portfolio, nuclear medicine physicians can test new strategies for disease assessment therapy. For decades, meta-iodobenzylguanidine (mIBG) has been used evaluate extent when coupled with iodi...

the primary treatment of thyroid carcinoma is surgery and the outcome depends on its extent. the post-operative management alternatives in thyroid carcinoma include thyroid hormone, radio-iodine ablation (i-131 na), external beam radiation therapy (ebrt) and occasionally adjuvant chemotherapy. this retrospective study analyzes the managements of 153 patients (102, 51), age range 10-96 years, me...

background: the aim of the study was to evaluate the third trimester urinary iodine excretion and to assess its relation with newborns thyroid function. materials and methods: a total  of  208 healthy third trimester pregnant women without previous history of thyroid disease were included in the study. urinary iodine levels of mothers were measured and neonatal tsh levels were screened on the 3...

background: goiter is thyroid enlargement, which is the most common visible symptom of iodine deficiency. some studies have shown iodine deficiency in water, soil, and food in many places worldwide. we aimed to determine the prevalence of goiter and the association between urine iodine levels in children with severity and prevalence of goiter in mountainous villages of kashan city (center of ir...

BACKGROUND There is a concern regarding the use of iodinated contrast agents (ICA) for chest and neck computed tomography (CT) to localize metastatases in patients with differentiated thyroid cancer (DTC). This is because the iodine in ICA can compete with (131)I and interfere with subsequent whole scans or radioactive iodine treatment. The required period for patients to eliminate the excess i...

malignant pleural effusion is a common complication in certain malignancies. pleurodesis is the best option most of the time. the purpose of this study was to compare the choice of belomycin with povidone-iodine, which is not only determined by the efficacy of the agent but also by its cost, accessibility, safety, ease of administration and the number of administrations to achieve a complete re...