BACKGROUND Hepcidin is a key regulator of iron homeostasis, but to date no studies have examined the effect of hepcidin on iron absorption in humans. OBJECTIVE Our objective was to assess relations between both serum hepcidin and serum prohepcidin with nonheme-iron absorption in the presence and absence of food with the use of dual stable-iron-isotope techniques. DESIGN The study group incl...

The structure of the iron-binding glycoprotein lactoferrin, present in milk and other exocrine secretions, has been elucidated in great detail, both the three-dimensional protein structure and the attached N-glycans. Structure-function relationships are being established. From these studies a function for lactoferrin in host defence and modulation of iron metabolism emerges. This paper describe...

The bulk of the cement industry's environmental burden is from calcareous source. Calcium mostly available naturally as limestone (CaCO3), where almost half mass eventually released CO2 during clinker manufacture. Iron (Fe) fourth most common element in Earth's crust surpassed only by oxygen, silicon, and aluminium; therefore, potential raw materials for alternative cements can contain signific...

Part of the rationale for this practice is the high iron requirement during pregnancy, almost 3 times that required for nonpregnant women of childbearing years, which is difficult to meet from dietary sources. Another reason for supplementation is that anemia caused by iron deficiency alone or in combination with other factors, eg, folate deficiency, vitamin A deficiency, and malaria, has been ...

The development of iron granules in honey-bee tissues was investigated using both anatomical and analytical methods. Iron granules are present only in the trophocytes of post-eclosion adults and have the same elemental composition as those in foraging adults. The granules increase in both size and number during ageing. Iron levels in developing worker honey-bees were measured by proton-induced ...

Introduction: R2 and phase images derived from high-resolution 7 Tesla magnetic susceptibility-weighted MRI provide a rich contrast in healthy and diseased human brain. Yet, the sources that contribute to this contrast are not fully understood. Previous studies suggest that iron and myelin brain content may each contribute to R2 and phase in a different manner [1]. In this study, we used multip...