Inventory-routing problems (IRPs) arise in vendor-managed inventory systems. They require jointly solving a vehicle routing problem and an inventory management problem. Whereas the solutions they yield tend to benefit the vendor and customers, solving IRPs solely based on cost considerations may lead to inconveniences to both parties. These are related to the fleet size and vehicle load, to the...

Macrophages are essential for systemic iron recycling, and also control iron availability to pathogens. Iron metabolism in mammalian cells is orchestrated posttranscriptionally by iron-regulatory proteins (IRP)-1 and -2. Here, we generated mice with selective and combined ablation of both IRPs in macrophages to investigate the role of IRPs in controlling iron availability. These animals are hyp...

Bacillus subtilis aconitase, encoded by the citB gene, is homologous to the bifunctional eukaryotic protein IRP-1 (iron regulatory protein 1). Like IRP-1, B. subtilis aconitase is both an enzyme and an RNA binding protein. In an attempt to separate the two activities of aconitase, the C-terminal region of the B. subtilis citB gene product was mutagenized. The resulting strain had high catalytic...

Purpose: Previous studies have found mixed results regarding the effect of job crafting (JC) on employee engagement (EE) and performance (EP). JC was also influenced by type work tenure. Therefore, present study examined relationship between EE in increasing in-role (IRP) extra-role (ERP). Additionally, it analyses manufacturing service micro, small medium enterprise (MSME) differences Design/m...

Conventional electric production simulation models do not fully capture the unique issues surrounding wind power plants. PacifiCorp used an hourly system dispatch model to estimate wind resource integration costs in its Integrated Resource Plan (IRP). This paper explores a number of modeling issues surrounding the representation of wind integration costs in dispatch models and the implications ...

The Industrial Restructuring Project (IRP) was initiated at the beginning of 1996 as the KwaZulu-Natal Industrial Restructuring Project (KZN IRP). The project initially focused exclusively on KwaZulu-Natal, but is now aimed at supporting industrial policy in South Africa at the national, provincial and local levels. It is facilitated by international experts and is based at the School of Develo...

Intelligent Space based on ubiquitous computing is a space which has distributed sensory intelligence and is equipped with actuators. The various devices of ubiquitous sensory intelligence cooperate with each other autonomously, and the whole space has high intelligence, where we can easily interact with computers and robots, and get useful services from them. This paper gives an overview of a ...

El presente trabajo tiene por objetivo analizar los efectos del Impuesto a la Renta servicio de carácter personal (IRP) en el Paraguay periodo 2012-2016. La metodología empleada fue corte cuali-cuantitativo. Para ello, se inició revisión acervo bibliográfico existente, tanto nivel nacional como internacional, y también datos secundarios obtenidos instituciones gubernamentales. estudio 201...