نتایج جستجو برای: ischemic postconditioning

تعداد نتایج: 85574  

Journal: :Expert Review of Cardiovascular Therapy 2010

2012
Shogo Shimizu Darryl T. Martin Fotios Dimitriadis Keisuke Satoh Motoaki Saito

The primary pathophysiological event in testicular torsion is ischemia-reperfusion (I-R) injury, which is caused by the twisted spermatic cord and its release. Moreover, testicular torsion is most likely mediated by reactive oxygen species. Ischemic preconditioning (IPreC) is a phenomenon in which a prior ischemic stress renders the organ resistant to a subsequent ischemic insult. Ischemic post...

Journal: :American journal of physiology. Heart and circulatory physiology 2011
Shoji Sanada Issei Komuro Masafumi Kitakaze

Heart diseases due to myocardial ischemia, such as myocardial infarction or ischemic heart failure, are major causes of death in developed countries, and their number is unfortunately still growing. Preliminary exploration into the pathophysiology of ischemia-reperfusion injury, together with the accumulation of clinical evidence, led to the discovery of ischemic preconditioning, which has been...

2011
Meng Wei Ping Xin Shuai Li Jianping Tao Yapeng Li Jing Li Mingya Liu Jingbo Li Wei Zhu Andrew N. Redington

Rationale: Remote ischemic conditioning induced by repeated episodes of transient limb ischemia is a clinically applicable method for protecting the heart against injury at the time of reperfusion. Objective: To assess the effect of chronic, repeated, remote conditioning on infarct size and long-term remodeling after myocardial infarction. D espite the timely application of reperfusion therapy,...

2012
Xiaoyu Song Hongde Xu Yanling Feng Xiaoman Li Meina Lin Liu Cao

BACKGROUND Hepatic ischemia and reperfusion injury (IRI) is a major complication in liver surgery, and hepatic steatosis is a primary factor aggravating cellular injury during IRI. Both pro-inflammatory cytokines and reactive oxygen species (ROS) are key mediators of hepatic IRI. Ischemic preconditioning (IpreC), remote ischemia preconditioning (RIPC) and ischemic postconditioning (IpostC) have...

Journal: :Circulation 2008
Hélène Thibault Christophe Piot Patrick Staat Laurence Bontemps Catherine Sportouch Gilles Rioufol Thien Tri Cung Eric Bonnefoy Denis Angoulvant Jean-François Aupetit Gérard Finet Xavier André-Fouët Jean Christophe Macia Franck Raczka Rolland Rossi Rolland Itti Gilbert Kirkorian Geneviève Derumeaux Michel Ovize

BACKGROUND We previously demonstrated that ischemic postconditioning decreases creatine kinase release, a surrogate marker for infarct size, in patients with acute myocardial infarction. Our objective was to determine whether ischemic postconditioning could afford (1) a persistent infarct size limitation and (2) an improved recovery of myocardial contractile function several months after infarc...

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