BACKGROUND Urinary 8-iso-PGF2α, a marker of oxidative stress, is influenced by the activation of NOX2. It is unclear if platelets 8-iso-PGF2α contribute to urinary 8-iso-PGF2α. METHODS AND RESULTS In a cross-sectional study, platelet, urinary, and serum 8-iso-PGF2α were determined in subjects with downregulation (X-linked chronic granulomatous disease [X-CGD], n=25) and upregulation (type II ...

Endothelin-1 (ET-1) is elevated in patients with atrial fibrillation (AF) and heart failure. We investigated effects of ET-1 on human atrial cellular electrophysiological measurements expected to influence the genesis and maintenance of AF. Action potential characteristics and L-type Ca(2+) current (I(CaL)) were recorded by whole cell patch clamp, in atrial isolated myocytes obtained from patie...

reliability of a system is the probability that it will function as intended for the required period of time. the opposite of reliability is failure probability per unit time or over time, such as a life cycle. following a review of existing reliability codes and approaches, comprehensive approaches to assess the reliability of offshore structures are described, including probabilistic analysis...

the risks of fire and explosion in oil and gas industry need to be managed. the objectives of the present study were to assess the risk of fire and explosion in iso-max unit of tehran oil refinery using dow’s fire and explosion index and to study the influences of the controlling methods. the latest version of dow fire and explosion index guideline was applied to calculate the fire and explosio...

For investigation of the properties of smooth muscle contraction hypertonically added 40 mm K medium has been used as a routine in this laboratory. Others have used isotonic high K/Na deficient medium for the same purpose. The distinct difference xisting between the mechanical response of guinea pig taenia coli in hyper-40 K medium and that in iso 152 K medium has been reported earlier. The res...

MARK C. PAULK Software Engineering Institute he Capability Maturity Model T Model for Software, developed by the Software Engineering Institute, and the ISO 9000 series of standards, developed by the International Organization for Standardization, have the common concern of quality and process management. The two are driven by similar issues and are intuitively correlated, but they differ in th...

In this paper, we describe the LIA system proposed for the MediaEval 2013 Crowdsourcing for Social Multimedia task. The aim is to associate an accurate label to an image among multiple noisy labels collected from a crowdsourcing platform. In particular, the task participants have to predict two types of binary labels for each considered image. The first one mentions that an image is truly fashi...