The aim of research was to study parameters homeostasis and conditions for stable operation the autoperfused heart-lung complex ex vivo.Materials methods. A series acute experiments (n-3) carried out create a functioning vivo. large mammal (mini-pig weighed 20-30 kg) used as an experimental model. During experiment, invasive blood pressure in aortic root, pulmonary artery, central venous pressu...

Blood pressure increases will increase heart rate in intact chick embryos, prior to the development of neural control. Similarly, in surgically isolated hearts, increases in intraventricular fluid pressure will increase the rate of beat. However, fluid pressure applied equally to both interior and exterior surfaces of the isolated heart does not result in increased heart rate. Therefore, we con...

The purpose of this study was to determine the role of streptococcal M protein in naturally-occurring CD4+CD25+ regulatory T cells (nTregs) function and development in rheumatic heart disease in Iraqi patients. Streptococcus pyogenes was isolated for subsequent M protein extraction. Also, peripheral blood nTregs and CD4+ T cells were isolated by using Magnetic Cell Separation System. Tissue cul...

UNLABELLED The assessment of myocardial radiotracer kinetics, including cardiac extraction fraction and washout, requires the study of isolated perfused hearts to avoid analytic error due to tracer recirculation and systemic metabolites. Analysis of the isolated perfused rat heart by a high-resolution small-animal PET system may offer both reliable evaluation of cardiac tracer kinetics and tomo...

myocardial performance, utilizing the isolated canine heart preparation, was studied in two groups: normal control dogs and those subjected to hemorrhagic shock. a marked deterioration in myocardial functional capacity was observed in the shock group. from this study, myocardial incapacity resulting from the period of acute hypotension is felt to be a contributing factor in the death of animals...

in this study, we investigated the cardioprotective effects of resveratrol. rats were intraperitoneally administered with resveratrol (25 mg/kg bw) or vehicle (ethanol 10%) for 7 days and their heart subjected to ischemia/reperfusion injury. isolated hearts were langendorff perfused, left ventricular functions as heart rate and developed pressure, as well as, heart antioxidant status were deter...

objective: several studies have shown that chichorium intybus l. (c. intybus) which possesses flavonoid compounds has an effective role in treatment of cardiovascular diseases. contractile dysfunction mostly occurs after acute myocardial infarction, cardiac bypass surgery, heart transplantation and coronary angioplasty. the aim of the present study was to investigate the effect of aqueous extra...

Cardiac tamponade is a life-threatening condition related to fluid accumulation within the pericardial sac that impairs normal cardiac filling. As accumulates in space, pressure rises. This increase transmitted across transmural and when it exceeds intracavitary pressures, collapse of chambers occurs. In circumferential effusions, bilateral typically occurs, sequence chamber corresponds with lo...