نتایج جستجو برای: isoliquiritigenin

تعداد نتایج: 260  

2016
Minna Wu Yaqi Wu Baoguo Deng Jinsong Li Haiying Cao Yan Qu Xinlai Qian Genshen Zhong

Imbalances in intestinal bacteria correlate with colitis-associated colorectal cancer (CAC). Traditional Chinese medicines have been used to adjust the gut microbiota, and isoliquiritigenin (ISL), a flavonoid extracted from licorice, has shown antitumor efficacy. In this study, the effects of ISL on CAC development and the gut microbiota were evaluated using an azoxymethane and dextran sulphate...

2013
Xiaoyu Zhang Ping Zhu Xiuying Zhang Yina Ma Wenguang Li Ji-Mei Chen Hui-Ming Guo Richard Bucala Jian Zhuang Ji Li

Isoliquiritigenin (ISL), a simple chalcone-type flavonoid, is derived from licorice compounds and is mainly present in foods, beverages, and tobacco. Reactive oxygen species (ROS) is a critical factor involved in modulating cardiac stress response signaling during ischemia and reperfusion. We hypothesize that ISL as a natural antioxidant may protect heart against ischemic injury via modulating ...

2017
Lingling Si Xinhui Yang Xinyan Yan Yanming Wang Qiusheng Zheng

The aim of the present study was to investigate whether an increase in cyclin-dependent kinase 2 (CDK2) activity is involved in apoptosis of human bladder cancer T24 cells induced by isoliquiritigenin (ISL). The viability of T24 cells was estimated using a sulforhodamine B assay. Cell morphological changes were examined using Hoechst 33258 staining. The apoptotic rate was determined by staining...

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