OBJECTIVES Our objective is to test the hypothesis that coronary endothelial function (CorEndoFx) does not change with repeated isometric handgrip (IHG) stress in CAD patients or healthy subjects. BACKGROUND Coronary responses to endothelial-dependent stressors are important measures of vascular risk that can change in response to environmental stimuli or pharmacologic interventions. The eval...

Bromocriptine (Br) was used to test the hypothesis that central dopaminergic mechanisms modulate sympathetic nerve tone, and that when dopaminergic control is deficient there may result enhanced noradrenergic activity and elevated blood pressure (BP) in some patients with primary hypertension. Seven hypertensive patients (age 29 ± 3 years) were studied after a single oral dose of Br (2.5-5.0 mg...

Background. Abdominal fat accumulation, also known as central obesity, is a major risk factor for many degenerative diseases, including cardiovascular disease and diabetes. Isotonic and isometric workouts can be used to avoid the buildup of fat in the belly, and young ladies should measure their waist circumference regularly. Objectives. This study showed how isotonic and isometric exercise af...

Findings of the studies on relationship between isometric handgrip contraction and changes in cerebral blood flow (CBF) are contradictory. The aim study was to evaluate CBF during one minute a maximal contraction. Our main hypothesis that test will cause decrease related strength. protocol included transcranial Doppler ultrasound measurement middle arterial mean velocity (Vmean) with concomitan...

Exercising at submaximal intensity with a hand dynamometer causes mild hemodynamic adaptations that can improve cardiovascular function. However, responses and fatigue have not been adequately studied in an isometric exercise protocol combined blood flow restriction (BFR). Our study aimed to examine compare acute muscle after session using handgrip dynamometer, without BFR. Twelve volunteers pe...