BACKGROUND Plaque psoriasis is a chronic disease characterized by scaly plaques on the skin that can itch and bleed. Psoriasis covering over 10% of the body is classified as moderate to severe, and can impact patient quality of life. OBJECTIVES To assess the relationship between plaque psoriasis self-reported severity symptoms and health-related quality of life, work productivity, and activit...

To verify the usefulness of moisturizers, a multi-center study was conducted on patients with atopic dermatitis who visited 3 university hospitals in Japan between November 2009 and March 2012. Thirty-seven patients with dry skin and stable symptoms who were receiving topical and oral treatments were given moisturizers for 8 weeks. The moisturizers contained components such as glycerin and seaw...

BACKGROUND Hypertrophic scar following a burn is caused by the excessive deposit of collagen resulting in an exaggerated wound healing response. The burn patient complains of pain and itching over the scar, which can give rise to cosmetic and functional problems. OBJECTIVE The aim of this study was to investigate the clinical and histological correlation of a hypertrophic burn scar for itchin...

Abstract Introduction Health-related quality of life (HRQL) is an important outcome in burn care and research. An advantage a generic HRQL instrument, like the EQ-5D, that it enables comparison outcomes with other conditions general population. However, downside does not include specific domains, scar issues or itching. Adding extra items to instrument might overcome this issue. This study expl...

BACKGROUND The aim of our study was to investigate effects of 6-week pretreatment of seasonal allergic rhinitis (AR) with cetirizine, and montelukast, alone and in combination. Antihistamine/antileukotriene treatment is effective in AR. Antihistamines may prevent AR symptoms while prophylactic activity of antileukotrienes remains unclear. METHODS Sixty AR patients, aged 18-35 years, were rand...

OBJECTIVE To assess the effectiveness of sodium hyaluronate Eye Gel in Dry Eye Disease (DED) patients Methods: A Multi-center, Open-label, Uncontrolled clinical trial was conducted in different centers of Pakistan. Ten ophthalmologists conducted this study in which 250 diagnosed patients with dry eye disease were enrolled after obtaining a written informed consent. Ten patients were dropped out...

PURPOSE Two individual phase 3 conjunctival allergen challenge (CAC) studies of similar design have assessed the efficacy and safety of olopatadine hydrochloride (HCl) 0.77% for the treatment of allergic conjunctivitis. The purpose of this study is to evaluate the integrated efficacy and safety of olopatadine HCl 0.77% from a larger dataset by pooling data from the two individual CAC studies. ...

Pruritus is the most burdensome symptom of atopic dermatitis (AD). A novel 11-point caregiver-reported worst scratch/itch numeric rating scale (WSI NRS; from 0 [no itching] to 10 [worst itching possible]) assess pruritus in young patients with moderate-to-severe AD was developed and evaluated. Qualitative interviews were conducted 24 caregivers children aged 6 months <6 years evaluate content v...

Itchy scalp troubles many people. The causes of itching can be systemic, psychogenic, neurological, and dermatological diseases. most common diseases associated with are seborrheic dermatitis psoriasis. pathogenesis these is very different, but in both cases, skin microbiota changes may present, supporting the inflammation. Also, conditions, flaking other similar clinical presentations occur. I...

 Abstract  Background: Human infestation to ectoparasites such as ticks, lice, cimex, fleas, mites and others agents may result in intensive allergic reaction with symptoms of itching, skin infection and severe irritation. In this case report, we present a case of dermatitis caused by cat flea. Case presentation: A three-member family referred to dermatology clinic in Babol due to dermal co...