نتایج جستجو برای: itpa
تعداد نتایج: 206 فیلتر نتایج به سال:
Multilocus genotypes have been shown to be of relevance for using pharmacogenomic principles to individualize drug therapy. As it relates to thiopurine therapy, genetic polymorphisms of TPMT are strongly associated with the pharmacokinetics and clinical effects of thiopurines (mercaptopurine and azathioprine), influencing their toxicity and efficacy. We have recently demonstrated that TPMT and ...
ation in human cancer. Cancer Res 2000;60:4366–71. 15. Esteller M, Corn PG, Urena JM, Gabrielson E, Baylin SB, Herman JG. Inactivation of glutathione S-transferase P1 gene by promoter hypermethylation in human neoplasia. Cancer Res 1998;58:4515–8. 16. Esteller M, Hamilton SR, Burger PC, Baylin SB, Herman JG. Inactivation of the DNA repair gene O-methylguanine-DNA methyltransferase by promoter h...
Within the ITPA Topical Group on Energetic Particles, we have investigated the impact that various mechanisms breaking the tokamak axisymmetry can have on the fusion alpha particle confinement in ITER as well as on the wall power loads due to these alphas. In addition to the well-known TF ripple, the 3D effect due to ferromagnetic materials (in ferritic inserts and test blanket modules) and ELM...
Abstract In this work, we focus on the development of particle-in-cell scheme and its application to studies Alfvén waves energetic particle (EP) physics in tokamak plasmas. The δ f full f schemes are formulated same footing adopting mixed variables pull...
BACKGROUND Working memory. AIM To verify the performance of working memory abilities and their relation with the severity of phonological disorders. METHOD 45 children, with ages between 5.0 and 7.11 years, with evolutional phonological disorders (EFD), 17 female and 18 male, were evaluated. All subjects were assessed using the Child Phonological Evaluation proposed by Yavas et al. (1991). ...
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