Laboratory tests revealed the following values: hemoglobin, 10.8 g/dL (6.4 mmol/L), with an RBC smear showing several Howell-Jolly bodies and burr cells; WBCs, 2.7 X 10 thrombocytes, 36 X 10 with coagulation tests indicating severe disseminated intravascular coagulation; glucose, 14.3 mg/dL (0.8 mmoIlL); creatinine, 3.9 mg/dL (345 f.LmollL), and serum lactate, 99.2 mg/dl. (11.9 mmol/L). A chest...

CASE REPORT A male Domestic Short-hair cat was presented for chronic weight loss, lethargy and hyporexia. Complete haematological examination revealed non-regenerative anaemia, neutropenia and thrombocytopenia, as well as Howell-Jolly bodies, anisocytosis, polychromasia and macrocytosis on blood smear evaluation. Histopathological evaluation of bone marrow biopsy disclosed hypocellularity consi...

The blood picture of children with sickle-cell anaemia was found to change with age. The changes were most marked in the first year but the mean level of haemoglobin, haemoglobin F, and target cells fell until adolescence, and irreversibly sickled cells rose. Reticulocytes, Howell Jolly bodies, and normablasts altered little after one year. The fall in haemoglobin F suggested a delayed changeov...

Clinical supervision is the least investigated, discussed and developed aspect of clinical education (Kilminster & Jolly, 2000) despite being essential within initial professional training and mandated by governments. Even the basic concepts lack precision (Martin, Kumar, & Lizarondo, 2017; Milne, 2007; White, 2017). A popular form of supervision is peer supervision, especially peer group super...

Thrombocytosis is a common feature of myeloproliferative disorders but may also result from various conditions including chronic iron deficiency, hemorrhage, chronic inflammation and splenectomy. We report two cases of secondary thrombocytosis caused by isolated and congenital asplenia, mimicking essential thrombocythemia. These two adult cases of spleen agenesis were unexpected. We conclude th...

A total of 15 morphological abnormalities characteristic of dyserythropoiesis were evaluated in bone marrow smears stained with May-Grunwald-Giemsa stain. Abnormalities were classified as: (a) anomalies of the nucleus (binuclearity, multinuclearity, nuclear lobulation, budding, fragmentation, chromatin lumping and pyknosis, intranuclear bridging, extrusion of the nucleus); and (b) anomalies of ...

*Dr Rachel E Jordan [email protected] *Prof Peymané Adab [email protected] Alice Sitch [email protected] Dr Alexandra Enocson [email protected] Deirdre Blissett [email protected] Dr Sue Jowett [email protected] Dr Jen Marsh [email protected] Prof Richard Riley [email protected] Prof Martin R Miller [email protected] Dr Brendan G Cooper [email protected] Dr Al...