© 2018 Indian Dermatology Online Journal | Published by Wolters Kluwer Medknow Post Kala‐azar dermal leishmaniasis (PKDL) is a late cutaneous manifestation of untreated or partially treated visceral leishmaniasis (VL) and is caused by the same organism, i.e., Leishmania donovani. It characteristically manifests as macules, nodules, plaques, and facial erythema. A 19‐year‐old male presented with...

In the 19(th) century, a devastating epidemic of visceral leishmaniasis (kala-azar) swept through northeast India. After identification of the pathogenic agent, Leishmania donovani, in 1903, the question of its transmission remained to be resolved. In 1904, thanks to work by L. Rogers on cultures of this parasite it became probable that a haematophagous arthropod was responsible for transmissio...

Sir, Post kala-azar dermal leishmaniasis (PKDL) is a wellrecognized sequel of kala-azar in India, developing in approximately 20% cases after a variable time interval of 1 – 5 years (1). The disease occurs chiefly in the eastern parts of India, an area that also has a high prevalence of leprosy. PKDL manifests as symmetrically distributed hypopigmented macules, papules, infiltrated plaques and ...

mammalian hosts (9). Drug resistance or sensitivity is based on sequences of M2 and NA. Substitution within residues including L26I, V27A/I, A30S, and S31N of the M2 ion channel protein was used to predict amantadine-resistant mutants, and H274Y of the NA was used to predict for oseltamivir resistance (10). The virus observed in 2006 isolates from Phichit was resistant to amantadine but sensiti...

From the records of the number of fresh cases of kala-azar in the different districts for the last thirty years (table II and the charts), it will be found that epidemics of kala-azar have occurred in different districts of Assam at intervals of about 7 to 10 years and have lasted for about ten years each time. The charts show two distinct epidemic waves during the last thirty years in Sibsagar...

Post-kala-azar dermal leishmaniasis (PKDL) is a dermatologic manifestation that usually occurs after visceral leishmaniasis (VL) caused by Leishmania donovani. It is characterized by hypopigmented patches, a macular or maculopapular rash and nodular skin lesions on the body surface. Involvement of the mucosae is very rare and unusual in PKDL. We report a case of PKDL that presented with polymor...