background: non-ketotic hyperglycemia (nkhg) may increase the probability of seizures and movement disorders. methods: we describe  a series of 14 elders admitted for seizures and movement disorders linked to nkhg. results: twelve  patients  developed motor  seizures  and two others movement disorders. glucose levels varied 9.28 to 32 mmol/l, while osmolarity values varied from 302.28 to 328  m...

This communication concerns two patients in whom spuriously enhanced SGOT (serum glutamic-oxaloacetic transaminase; L-aspartate: 2-oxoglutarate amino-transferase, EC 2.6.1.1), as determined by the SMA 12/60 AutoAnalyzer (Technicon Corp., Tarrytown, N.Y. 10591), led to erroneous diagnoses of liver disease. This error can be avoided by checking suspect supranormal SMA 12/60 values by ultraviolet ...

709 The patient was kept warm in bed and the rash gradually faded during the course of a week. The discoloration lightened through red and brown, and on discharge from hospital only slight residual staining remained. There was no evidence of a falling haemoglobin, and after discharge she suffered no further symptoms. The cold agglutinins, however, were still present after a month. When reviewed...

A study of 82 fatal cases of Friedreich's ataxia showed that over half the patients died of heart failure while nearly three-quarters had evidence of cardiac dysfunction during life. A high incidence of diabetes mellitus (23%) was another finding, and four patients developed diabetic ketosis terminally.

The metabolic effects of intraperitoneal administration of carbon tetrachloride (1ml/kg) were studied in starved rats. The most notable change in circulating substrates was an 80% fall in ketone-body concentrations, which was associated with the doubling of urinary nitrogen losses. The results demonstrate the importance of starvation ketosis in permitting fat mobilization to decrease effectivel...

Diabetic patients frequently encounter ketosis that is characterized by the breakdown of lipids with the consequent accumulation of ketone bodies. Several studies have demonstrated that reactive species are likely to induce tissue damage in diabetes, but the role of the ketone bodies in the process has not been fully investigated. In this study, electron paramagnetic resonance (EPR) spectroscop...