نتایج جستجو برای: keywords mefenamic acid
تعداد نتایج: 2689084 فیلتر نتایج به سال:
Background and Objective: Menorrhagia is considered as one of the most common gynecological problem at child-bearing age of women. Regarding the prevalence of this disease, this study examined the effect of Nettle extract in menorrhagia improvement by statistical modeling. Materials and Methods: The statistical modeling was performed by data collection from 100 patients with menorrhagia. One...
Objective(s): The aim of present study is to formulate mefenamic acid transdermal gel based on vesicular drug delivery approaches.Materials and Methods: For the preparation of mefenamic acid transdermal gel, transfersomes were selected as colloidal carriers. Transfersomes were prepared by hand shaking and thin film hydration techniques. The obtained transfersomes were characterized for vesicula...
* Author for correspondence and reprint requests Z. Naturforsch. 64c, 809-812 (2009); received May 7/July 23, 2009 Menthalactone, a new long-chain alkene with a bicyclic lactone moiety, was isolated as an analgesic constituent from the leaves of Mentha cordifolia Opiz. At a dosage of 100 mg/ kg mouse, it decreased the number of squirms induced by acetic acid by 67.3%. Statistical analysis using...
Ibuprofen and mefenamic acid are weak, competitive inhibitors of cyclooxygenase-2 (COX-2) oxygenation of arachidonic acid (AA) but potent, noncompetitive inhibitors of 2-arachidonoylglycerol (2-AG) oxygenation. The slow, tight-binding inhibitor, indomethacin, is a potent inhibitor of 2-AG and AA oxygenation whereas the rapidly reversible inhibitor, 2'-des-methylindomethacin, is a potent inhibit...
Non-steroidal Anti-inflammatory drugs (Aceclofenac, Mefenamic acid) have conjugated with different antioxidants such as Thymol, Menthol which having antiulcerogenic activity with the NSAIDsantioxidant mutual prodrug gastro sparing NSAIDs devoid of Ulcerogenic side effects. Two mutual Prodrugs have synthesized in which NSAIDs have been conjugated with different antioxidants by a glycolic acid sp...
the objective of this study was to formulate and evaluate the drug-polymer interaction of mefenamic acid (ma) using two polymers with different characteristics as ethylcellulose (ec) and/or cellulose acetate phthalate (cap). microspheres were prepared by the modified emulsion solvent evaporation (mese). the effect of drug-polymer interaction was studied for each of microspheres. important param...
In this work, the nickel-aluminum layered double hydroxide (Ni-Al LDH) with nitrate interlayer anion was synthesized and used as a solid phase extraction sorbent for the selective separation and pre-concentration of mefenamic acid prior to quantification by UV detection at λmax=286 nm. Extraction procedure is based on the adsorption of mefenamate anions on the Ni-Al(NO3-) LDH and/or their excha...
Role of prostaglandins and nitric oxide on halothane-induced arteriolar dilatation in rat diaphragm.
The effects of anaesthetics on the microcirculation of the diaphragm are incompletely understood. Therefore, we assessed by in vivo intravital microscopy in rats the action of halothane on diaphragmatic arteriolar diameter and the role of nitric oxide and prostaglandins on halothane-induced diaphragmatic arteriolar diameter. We studied 54 rats anaesthetized with thiopentone. Dose-response curve...
Abstract Chromate ions CrO 4 −2 have been used in three simples, rapid, an accurate spectrophotometric method. These methods were suggested to estimate mefenamic acid its pure form and pharmaceutical preparations. different from each other with reactants components, they are similar as, indirect depends on oxidation – reduction reaction. So that, Method 1, based reaction between chromate ion pr...
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