Limitations regarding process design, optimization, and control often occur when using particular simulators. With the implementation of connection methodologies, integrated tools could be made by coupling popular simulation software with each other or programming environments. In current paper, we summarized categorized existing research application multi-software engineering in chemical indus...

Systems biology provides new approaches for metabolic engineering through the development of models and methods for simulation and optimization of microbial metabolism. Here we explore the relationship between two modeling frameworks in common use namely, dynamic models with kinetic rate laws and constraint-based flux models. We compare and analyze dynamic and constraint-based formulations of t...

The mean energy W expended in a collision of electrons with atmospheric gases is a useful parameter for fast aeronomy computations. Computing this parameter in transport kinetic models with experimental values can tell us more about the number of processes that have to be taken into account and the uncertainties of the models. We present here computations for several atmospheric gases of planet...

How to design a robust gene network to tolerate more intrinsic kinetic parameter variations and to attenuate more extrinsic environmental noises to achieve a desired filtering level will be an important topic for systems biology and synthetic biology. At present, there is no good systematic design method to achieve robust gene network design. In this study, a gene network suffering from intrins...

Submitted for the MAR05 Meeting of The American Physical Society Topological Singularities and Transport in Kicked Harper Model1 INDUBALA SATIJA, George Mason Univ — Quasienergy spectrum of kicked Harper model is found to exhibit a series of diabolic crossings. These conical degeneracies reside mostly on the symmetry line of its two-dimensional parameter space and their location is found to coi...

An original reaction mechanism and kinetic parameter estimation has been achieved for lomustine, an anti-cancer active pharmaceutical ingredient (API).