Background: The rice weevil, Sitophilus oryzae and rice moth, Corcyra cephalonica are major and cosmopolitan insect. Adults of S. oryzae (male and female) and both larvae are insatiable feeders on a great variety of grains. Objective: This study was conducted to estimate the insecticidal effect of essential oils from peppermint, Mentha piperita L. and black pepper, Piper nigrum L. ag...

BACKGROUND Leishmaniasis is an important public health disease in many developing countries as well in Iran. The main objective of this study was to investigate on leishmania infection of wild caught sand flies in an endemic focus of disease in Esfarayen district, north east of Iran. METHODS Sand flies were collected by sticky papers and mounted in a drop of Puri's medium for species identifi...

background: the mechanisms of virulence and species differences of leishmania parasites are under the influence of gene expression regulations at posttranscriptional stages. in iran, l. major and l. tropica are known as principal agents of cutaneous leishmaniasis, while l. infantum causes visceral leishmaniasis. methods: as a preliminary study, we compared the proteome mapping of the above thre...

Protective immunity against Leishmania major is provided by s.c. immunization with a low dose of L. major promastigotes or with dihydrofolate-thymidylate synthase gene locus (DHFR-TS) gene knockout L. major organisms. Whether these vaccine strategies will protect against infection with other Leishmania species that elicit distinct immune responses and clinical syndromes is not known. Therefore,...

abstract        background and objective: leishmania major is a flagellate protozoan parasite causing cutaneous leishmaniasis. although pentavalent antimony compounds are the first-line drugs for leishmaniasis, their application is often accompanied by numerous limitations and side effects. therefore, it is necessary to seek drugs of herbal origin that have fast-acting benefits and few side eff...

Background: NPs (NPs) with unique chemical and physical properties can be used for therapeutic purposes because of their strong antimicrobial activates. NPs have been used as an antimicrobial agents to inhibit microbial growth.Objectives: In view of the strong antimicrobial activity of NPs, the biogenic synthesis and leishmanicidal activity of rod-shaped ...

Background and objectives: Cutaneous leishmaniasis is endemic in most areas of Iran, and the diagnosis of its species is essential for controlling the disease. Leishmania major is the causative agent for cutaneous leishmaniasis in humans. Molecular methods are generally more sensitive than microscopic methods. The present study aimed to use a polymerase chain reaction-enzyme linked immunosorben...