The hemodynamic response to mental stress (mental arithmetic) was studied in adolscents with varying risk factors for essential hypertension (EH), One group (genetic) consisted of normotensive well adolescents who had at least one parentnt with EH. Another group (labile) consisted of adolescents with labile hypertension each of whom also had at least one pare with EH. The control population con...

Abstract Complex [( DIPeP BDI)Ca] 2 (C 6 H ), with a C 2− dianion bridging two Ca 2+ ions, reacts benzene to yield (biphenyl) biphenyl ( BDI=HC[C(Me)N‐DIPeP] ; DIPeP=2,6‐CH(Et) ‐phenyl). The complex was also prepared by reacting ) or reduction of BDI)CaI] KC 8 in presence biphenyl. Benzene‐benzene coupling observed when the deep purple product ball‐milling DIPP BDI)CaI(THF)] K/KI extracted (DIP...

Control of native enzyme levels is important when optimizing strains for overproduction of heterologous compounds. However, for many central metabolic enzymes, static knockdown results in poor growth and protein expression. We have developed a strategy for dynamically modulating the abundance of native enzymes within the host cell and applied this to a model system for myo-inositol production f...

Labile blood pressure elevation is believed to have less clinical significance than "fixed hypertension." This assertion was examined in the Framingham cohort of 5209 men and women followed for 20 years for the development of cardiovascular events in relation to three routinely measured blood pressures at each of 10 biennial examinations. Variability of pressure judged from the standard deviati...

The isolation of N10 formylfolic acid' from natural materials has been reported by several groups of workers (Rauen et al., 1952; Rauen and Jaenicke, 1953; Greenberg, 1954a; Silverman et al., 1954). It was concluded that the compound had been derived either from the degradation of a labile intermediate involved in the conversion of a bound (microbiologically inactive) form of folic acid in live...