Water bodies worldwide have proven to be vast reservoirs of clinically significant antibiotic resistant organisms. Contamination waters by anthropogenic discharges is a contributor the widespread dissemination resistance. The aim this research was investigate multiple different sources on national scale for role they play in environmental propagation A total 39 water and 25 sewage samples were ...

Background: Carbapenem-resistant Enterobacteriaceae (CRE) has become a public health threat due to resistance multiple antibiotics. The production of β-lactamase is the most important mechanism Enterobacteriaceae. Although isolates producing KPC-2 or NDM-1 enzymes have been reported widely, co-producing KPC-2, NDM-1, TEM-1, TEM-95, SHV-66, and other β-lactamases rarely detected in same strain, ...

Background: Diabetic foot infection (DFI) is an in soft tissue or bone patient with diabetes mellitus, Citrobacter species are infrequent nosocomial pathogens and cause a range of infections. the aim current study we report isolation carbapenem genes among isolated from DFI. Methods: about 111 swabs specimen were collection suspected DFI during period study, determine antibiotic susceptibility ...

This study aimed to evaluate the prevalence of carbapenemase-producing Enterobacteriaceae in Luanda, Angola. A total of 157 rectal samples were collected from children visiting a pediatric hospital in Luanda in March 2015. Fifty-seven imipenem-nonsusceptible enterobacterial isolates were recovered, most of which were non-clonally related. The blaOXA-181 (50/57) and blaNDM-1 (7/57) carbapenemase...

The NDM-1 gene is a significant public health concern. Acinetobacter is one of the most prevalent opportunistic pathogens causing recent nosocomial infections with NDM-1, and drug-resistant strains pose serious threats to public health worldwide. Herein, we present the genomic sequence of Acinetobacter calcoaceticus subsp. anitratus XM1570, a multidrug-resistant isolate that carries the blaNDM-...

The emergence of multiple-carbapenemase-producing Acinetobacter strains has been a serious concern during the past decade. Here, we report the draft genome sequence of an Acinetobacter baumannii strain isolated from a Japanese patient with three acquired carbapenemase genes: blaNDM-1, blaTMB-1, and blaOXA-58.

Background: The emergence and spread of metallo-beta-lactamase (MBL)-producing Klebsiella pneumoniae are growing global public health concerns. One the most common mechanisms carbapenem resistance is production MBLs, including Verona integron-encoded (VIM), New Delhi (NDM) imipenemase (IMP). Objectives: This study aimed to investigate MBLs among K. isolates. Methods: In this study, 240 isolates...

OBJECTIVES The aim of this study was to detect the presence of IgG against Moraxella catarrhalis β-lactamase in healthy adults, and to determine whether outer membrane vesicles (OMVs) could protect the enzyme from inhibition by anti-β-lactamase IgG. METHODS Transmission electron microscopy was used to detect the presence of β-lactamase in OMVs. Sera were examined by ELISA for specific IgG dir...

Nosocomial infections caused by Acinetobacter spp. resistant to carbapenems are increasingly reported worldwide. Carbapenem-resistant Acinetobacter (CRA) is becoming a serious concern with increasing patient morbidity, mortality, and lengths of hospital stay. Therefore, the rapid detection of CRA is essential for epidemiological surveillance. Polymerase chain reaction (PCR) has been extensively...