The lymphocyte activation gene-3 (LAG-3), selectively transcribed in human activated T and NK cells, encodes a ligand for major histocompatibility complex (MHC) class II molecules. Like CD4, LAG-3 ectodomain is composed of four Ig-like domains (D1-D4). Nothing is known about the LAG-3 regions or residues required to form a stable MHC class II binding site. In contrast to CD4, soluble LAG-3 mole...

Temporal ventriloquism refers to the phenomenon that a sound presented in close temporal proximity of a visual stimulus attracts its perceived temporal occurrence. Here, we investigate the time-course of the neuronal processes underlying temporal ventriloquism, using event-related brain potentials. To measure shifts in perceived temporal visual occurrence, we used a paradigm in which a sound mo...

This paper examines saturated control of a general class of uncertain nonlinear systems with timedelayed actuation and additive bounded disturbances. The bound on the control is known a priori and can be adjusted by changing the feedback gains. A Lyapunov-based stability analysis utilizing Lyapunov–Krasovskii (LK) functionals is provided to prove uniformly ultimately bounded tracking despite un...

The Hankel operator of the system with single control input delay is established by using state-space formulation in this paper. In general, this type of operator is not a compact one. Singular values of this type of operator are studied. Two examples are used to illustrate the computation of Hankel singular value by the theoretical method proposed in this paper.

This paper is concerned with the robustness of the predictor feedback control of linear systems with input delays. By applying certain equivalent transformations on the characteristic equation associated with the closed-loop system, we first transform the robustness problem of a predictor feedback control system into the stability problem of a neutral time-delay system containing an integral op...

The conversion from discrete-time to continuous-time models is sometimes quite troublesome. This paper answers related pending questions concerning z-domain poles at the origin, and relating them to s-domain models with time delay. Special attention is devoted to the tradeoff between fractional delay and direct feed-through. The paper places these questions into a general framework of model map...

S AbstractWe analyze the robust stability of Inverse LQ regulators for single-input linear systems with uncertain input delay. Unlike the usual LQ regulator, the Inverse LQ regulator has a gain tuning parameter that can be chosen freely to some extent without losing its LQ optimality. Utilizing this freedom we seek the range of tuning parameter that ensures the robust stability against the unce...