INTRODUCTION Langerhans cell histiocytosis (LCH) is a rare atypical cellular disorder characterized by clonal proliferation of Langerhans cells leading to myriad clinical presentations and variable outcomes. It usually occurs in children and young adults. It can be present with local and systemic manifestation involving skin, bone, mucosal tissues and internal organs. AIMS AND OBJECTIVES The ...

Received 2/6/2007; revised 4/25/2007; accepted 4/27/2007. For correspondence or reprints contact: Wan-Yu Lin, M.D., Department of Medical Imaging, Taichung Veterans General Hospital. 160 Section 3, Taichung Harbor Road, Taichung 407, Taiwan. Tel: (886)4-23741349, Fax: (886)4-23741348, E-mail: wylin@ vghtc.gov.tw Langerhans’ cell histiocytosis (LCH) is a proliferative histiocytosis disorder. The...