This study investigated the factors affecting the surgical treatment effect on patients with laryngeal cancer. The clinical data (including the sex, age, smoking index, drinking, primary tumor site, tumor (T) stage, lymph nodes (N) stage, tumor differentiation degree, tumor diameter, surgical method, lymph node metastasis and cervical lymph node dissection) of 215 patients with laryngeal cancer...

Laryngeal tuberculosis (TB) is a rare form of that most commonly presents with dysphagia and weight loss. We report case 75-year-old Vietnamese male who presented dysphagia, odynophagia, 30-pound loss over the two months prior to presentation. Nasopharyngeal evaluation with microdirect laryngoscopy was performed as part workup revealed lesions epiglottis left vocal cord. A tissue biopsy quantif...

1 Brimacombe J, Richardson C, Keller C, Donald S. Mechanical closure of the vocal cords with the laryngeal mask airway ProSeal. Br J Anaesth 2002; 88: 296–7 2 Kawauchi Y, Nakazawa K, Ishibashi S, Kaneko Y, Ishikawa S, Makita K. Unilateral recurrent laryngeal nerve neuropraxia following placement of a ProSeal laryngeal mask airway in a patient with CREST syndrome. Acta Anaesthesiol Scand 2005; 4...

We firstly conducted a case-control study to investigate the role of two SNPs in MLL3 gene (rs6943984 and rs4725443) in the development of laryngeal cancer in a Chinese population. Between May 2012 and October 2014, a total of 171 patients with laryngeal cancer and 251 control subjects were collected from the Zhumadian Central Hospital. Genotyping of MLL3 rs6943984 and rs4725443 were analyzed u...

OBJECTIVE To evaluate laryngeal sequelae from surgical treatment of recurrent respiratory papillomatosis in children, as well as associated risk factors. METHODS Case-control study. Medical record data analysis of 50 children with recurrent respiratory papillomatosis, divided into two groups: with and without laryngeal sequelae. The group of patients with laryngeal sequelae was compared to th...

BACKGROUND Tea and coffee are the most commonly consumed beverages in the worldwide. The relationship between tea and coffee consumption on the risk of laryngeal cancer was still unclear. METHODS Relevant studies were identified by searching electronic database (Medline and EMBASE) and reviewing the reference lists of relevant articles until Oct. 2013. Observational studies that reported RRs ...

OBJECTIVES To evaluate the significance of laryngopharyngeal reflux (LPR) as a risk factor in laryngeal cancer. METHODS We performed a case-control study with 29 consecutive laryngeal cancer patients who had undergone 24-hour ambulatory double pH monitoring from 2003 to 2006. The control group included 300 patients who had undergone 24-hour ambulatory double pH monitoring due to LPR-related s...

YY1 is a key transcription factor and plays different roles in various cancers. However, role and mechanism of YY1 in laryngeal cancer are still unknown. YY1 and MYCT1 mRNA and protein levels were detected by Real-time RT-PCR and Western Blot methods, respectively. Binding of YY1 to MYCT1 promoter was predicted and confirmed by bioinformatics and chromatin immunoprecipitation assays, respective...

OBJECTIVES/HYPOTHESIS To develop a reliable and safe laryngeal nerve conduction technique and to obtain consistent parameters as normal reference values. STUDY DESIGN A prospective single-arm study. METHODS A nerve conduction test was performed on the contralateral normal side in 42 patients with unilateral vocal fold palsy. The recording was performed in the intact thyroarytenoid muscle us...