An analysis of fluctuations of speech wave, i.e., pitch, amplitude, and waveform, is a subject of growing interest for improvement in the quality of synthesized voice. However, little information with respect to the sound source itself in speech production is available, since it is difficult to measure fluid and acoustic motions within the larynx. The purpose of the present study is to clarify ...

OBJECTIVE To compare pathologic results obtained via in-office transnasal fiberoptic laryngoscopy (TFL) to those of subsequent direct laryngoscopy in order to assess the accuracy of TFL as a diagnostic tool. PATIENTS One hundred and seventeen patients with suspicious laryngeal lesions. METHODS All patients underwent in-office biopsies. All patients with malignant diagnosis were referred to ...

Malignant mesenchymal tumors of the larynx constitute 0.3% to 1% of all laryngeal cancers. Of them, osteosarcoma is the rarest. Osteosarcoma of the larynx may be a difficult clinical diagnosis. Pathologic confirmation of osteoid is required for the diagnosis. Treatment is primarily surgical. It is believed that aggressive surgical intervention directed at complete tumor extirpation is the treat...

Chondrosarcoma of the larynx is a rare disease. The condition usually presents as a space-occupying lesion in the larynx. It is usually internal, but an external mass may be noted. Diagnosis demands a deep biopsy as the tumour is submucosal. Treatment is surgical, but the extent of this surgery is dependent upon the stage of the disease. The prognosis, in most cases, is usually very good. The l...

Abstract Background Histoplasmosis is an endemic granulomatous fungal infection which rarely infects the larynx; less than 100 cases have been reported in medical literature till date. Case presentation A 6-year-old female child, a diagnosed case of B cell acute lymphoblastic leukemia since past 2 years and on chemotherapy, presented with hoarseness dysphagia months. Direct laryngoscopy reveale...

Multiple imaging modalities are used to obtain qualitative and quantitative data on laryngeal height and state during pharyngeal consonant production. Videofluoroscopy provides insight into the relative changes in pharyngeal and epilaryngeal lumina, allowing us to compare the roles these structures play in epilaryngeal constriction. Simultaneous laryngoscopy and laryngeal ultrasound allow us to...

The simultaneous assessment of the status of the glottis opening and the position of the larynx can be beneficial for the diagnosis of disorders of voice production and swallowing. The method presented here makes use of a time-multiplex algorithm for the measurement of space-resolved transfer impedances through the larynx. The fast sequence of measurements allows a quasi simultaneous assessment...

OBJECTIVE To compare outcome of patients with advanced laryngeal hypopharyngeal squamous cell carcinoma treated surgically or with chemotherapy and/or radiotherapy. STUDY DESIGN Observational study. PLACE AND DURATION OF STUDY The Aga Khan University Hospital, Karachi, from January 2000 to December 2005. METHODOLOGY Medical records of already treated stage-III and IV squamous cell carcino...