PURPOSE To investigate the specific role of immune responses induced by lentogenic Newcastle disease virus (NDV) for its antitumor effect. MATERIALS AND METHODS NDV LaSota strain was used to infect the following human cells: non-small cell lung carcinoma (A549), glioblastoma (U87MG and T98G), mammary gland adenocarcinoma (MCF7 and MDA-MB-453), hepatocellular carcinoma (Huh7), transformed embr...

Newcastle Disease (ND) is a major viral disease in Indonesia. It is an RNA virus belongs to Paramyxovirinae. It is well known that RNA virus is easily to mutate. In some cases, this mutation could generate virulence alteration. It is noted that mutation of NDV which has avirulent amino acid sequence on the cleavage site, could mutate to be virulent Newcastle Disease Virus (NDV). It is needed to...

In an effort to protect chickens against Newcastle disease (ND), a nonreplicating virosome vaccine was produced by solubilization of Newcastle disease virus (NDV) with Triton X-100 followed by detergent removal with SM2 Bio-Beads. Biochemical analysis indicated that the NDV virosomes had similar characteristics as the parent virus and contained both the fusion and hemagglutinin-neuraminidase pr...

Newcastle disease (ND) is one of the most important diseases of poultry, negatively affecting poultry production worldwide. The disease is caused by Newcastle disease virus (NDV) or avian paramyxovirus type 1 (APMV-1), a negative-sense single-stranded RNA virus of the genus Avulavirus, family Paramyxoviridae. Although all NDV isolates characterized to date belong to a single serotype of APMV-1,...

We present a new scale U p (s < −t < 0 and 1 ≤ p < ∞) of anisotropic Banach spaces, defined via Paley–Littlewood, on which the transfer operator Lgφ = (g · φ) ◦ T−1 associated to a hyperbolic dynamical system T has good spectral properties. When p = 1 and t is an integer, the spaces are analogous to the “geometric” spaces Bt,|s+t| considered by Gouëzel and Liverani [26]. When p > 1 and −1 + 1/p...

Generic properties of different objects (functions, sets, measures, and many others) have been studied for a long time (see [1, 2, 3, 4, 5, 7, 8, 9, 10, 13, 15, 16]). We say that some property is generic (or typical) if the subset of all elements satisfying this property is residual. Recall that a subset of a complete metric space is residual if its complement can be represented as a countable ...

Authors Brian P. Rubin, MD, PhD, FCAP* Departments of Anatomic Pathology and Molecular Genetics, Cleveland Clinic, Lerner Research Institute and Taussig Cancer Center, Cleveland, Ohio Charles D. Blanke, MD, FACP British Columbia Cancer Agency and University of British Columbia, Vancouver British Columbia, Canada George D. Demetri, MD Dana-Farber Cancer Institute, Boston, Massachusetts Ronald P....

Two oil emuisified vaccines of Newcaslte disease were prepared from Lasota strain. The virus was propagated in 9-day-old chicken embryos through allantoic route. The haemagglutination titre of the allantoic fluid used for vaccine preparation was 2048. The fluid was inactivated by 0.1 per cent f nal concentration of formalin at 37 oc for 6 hours. Inactivated allantoic fluid was emulsified with a...