Exposure to high lead concentrations produces severe alterations in central nervous system development and, consequently, in the behavior of both experimental animals and children (l-5). However, in asymptomatic children exposed to lead intoxication the resulting intellectual and behavioral abnormalities may be expressed in different waysi.e., as hyperactivity (S), fine motor incoordination (7)...

Many US states now embrace the medical and recreational use of Cannabis. Changes in the laws have heightened interest and encouraged research into both cannabinoid products and the potential harms of Cannabis use, addiction, and intoxication. Some research into those harms will be reviewed here and misgivings about the use of Pregnenolone, to treat cannabis addiction and intoxication explained....

We report a man who developed oculogyric crisis one month after disulfiram intoxication. Brain MRI showed lesions involving bilateral globus pallidus and left substantia nigra. In our patient, neuronal discharges from pathologically reorganized basal ganglia circuit to the mid-brain ocular motor center might lead to tonic deviation of the eyes.

introduction: lead is one of the heavy metals that have adverse effects on blood cellsand hemopoiesis. in this study the ultrastructure of neutrophils in fetal rat spleen wereinvestigated following lead intoxication. material and methods: thirty female and 6 male sprague-dawley rats were chosenby simple random sampling. after mating the pregnant rats were classified into test and controlgroups....

A 4-year-old black boy was admitted to the hospital with vomiting, low-grade fever, and dehydration that were thought to be caused by viral gastroenteritis. He proceeded over the next 12 hours to rapidly deteriorate with brain herniation leading to brain death. The ultimate cause of death was found to be acute lead intoxication from a swallowed foreign body.

Lead exposure has been reported to produce many clinical features, including parkinsonism. However, its consequences on the circadian rhythms are still unknown. Here we aimed to examine the circadian rhythms of locomotor activity following lead intoxication and investigate the mechanisms by which lead may induce alterations of circadian rhythms in rats. Male Wistar rats were injected with lead ...

Lead intoxication in adults without occupational exposure is a rare and unexpected event. The case of a western European is reported who had severe anaemia after ingestion of several ayurvedic drugs, obtained during a trip to India. Laboratory findings showed high blood lead concentrations, an increased urinary lead concentration, and an increased urinary excretion of delta-aminolaevulinic acid...

background: unintentional drug intoxication is still a major cause of mortality and morbidity in young children. method & materials: in order to study changes of epidemiological indices of children intoxication during a 10-year period in hamadan province, all cases admitted to ghaem hospital from 1995-1999 were recruited, and compared with all cases admitted to the same hospital from 1990-1994....

abstract background: acute opium intoxication is one of the most common causes of poisoning in children in iran. although most cases are accidental, traditional misuse of opium for symptomatic therapy of various childhood diseases also contributes to high rate of opium intoxication in iran. cases: here, we report two cases of opium intoxication in infants resulted from transdermal application o...