The full n-Latin square is the n×n array with symbols 1, 2, . . . , n in each cell. In this paper we show, as part of a more general result, that any defining set for the full n-Latin square has size n3(1− o(1)). The full design N(v, k) is the unique simple design with parameters (v, k, (v−2 k−2 ) ); that is, the design consisting of all subsets of size k from a set of size v. We show that any ...

Studies of entanglement in many-particle systems suggest that most quantum critical ground states have infinitely more entanglement than noncritical states. Standard algorithms for one-dimensional systems construct model states with limited entanglement, which are a worse approximation to quantum critical states than to others. We give a quantitative theory of previously observed scaling behavi...

Abstract Haim–Munk syndrome (HMS) and Papillon–Lefevre (PLS) are rare, autosomal recessive palmoplantar keratodermas (PPKs) characterized by PPK periodontal inflammation. They phenotypic variants of clinically related syndromes caused homozygous or compound heterozygous mutations in cathepsin C (CTSC) on chromosome 11q14. Specific features HMS include pes planus, radiographic deformity the fing...

EFERENCES 1. Latib A, Colombo A. Bifurcation disease: what do we know, what should we do? J Am Coll Cardiol Intv 2008;1:218–26. 2. Popma J, Leon M, Topol EJ. Atlas of Interventional Cardiology. Philadelphia, PA: Saunders, 1994. 3. Spokojny AM, Sanborn TM. The bifurcation lesion. In: Ellis SG, Holmes DR, Strategic Approaches in Coronary Intervention. Baltimore, MD: Williams and Wilkins, 1996:288...

Anna Salerno #,1,2 , Alexis Delétoile #,1 , Martine Lefevre 1 , Ivan Ciznar 3 , Karel Krovacek 4 , 5 Patrick Grimont 1 and Sylvain Brisse 1* 6 7 8 9 10 # Contributed equally to this work 11 12 1 Unité Biodiversité des Bactéries Pathogènes Emergentes, Institut Pasteur, 28 rue du Docteur Roux, 75724 13 Paris Cedex 15, France 14 2 Department of Crop Systems, Forestry and Environmental Sciences, Un...

Those bacteria that cause the reddening of salted hides and salted fish, commonly designated as halophiles, grow more luxuriantly in laboratory media as the salt concentration increases from about 3 molar to saturation. This stimulative effect of sodium chloride has been observed and reported by Clayton (^)/ Robertson (6), Lockhead (5), and Stuart and James (13), Halophilic bacteria also have b...

This research investigated the role of adult mathematically-related talk and gesture on children’s numeracy development. Though mathematically-rich input provided by parents and teachers has been found to relate to children’s emergent numeracy skills (LeFevre, Clarke, & Stringer, 2002; Klibanoff et al., 2006), little is known about the role of gesture during math talk on children’s early mathem...

A variety of neutral serine proteases are important for the effector functions of immune cells. The neutrophil-derived serine proteases cathepsin G and neutrophil elastase are implicated in the host defense against invading bacterial and fungal pathogens. Likewise, the cytotoxic lymphocyte and NK cell granule-associated granzymes A and B are important for the elimination of virus-infected cells...