PURPOSE We evaluated the effectiveness of vitreous surgery for advanced stages of retinopathy of prematurity (ROP) with traction retinal detachment. METHODS Vitreous surgery was performed in 34 children (51 eyes) with total traction retinal detachment associated with stage 5 ROP between January 1989 and December 1991 at the Fukuoka University Hospital. The first phase of the procedure was com...

PURPOSE To report on pars plana vitrectomy (PPV) combined with pars plana lensectomy (PPL) with a preserved anterior capsule, panretinal endophotocoagulation (EPC) throughout the pars plana, and silicon oil (SO) tamponade (PPV + PPL + EPC + SO tamponade) for neovascular glaucoma (NVG). METHODS Thirteen eyes with NVG were treated. Ten eyes also underwent SO removal and intraocular lens (IOL) i...

OBJECTIVE To review our experience with Norrie disease to determine if early vitrectomy abrogates the natural history of this rare disease; namely, bilateral no light perception visual acuity and phthisis bulbi. METHODS We retrospectively reviewed the medical records of all patients seen in our tertiary care pediatric retinal clinical practice from 1988 through 2008 with a potential diagnosis...

PURPOSE To identify and determine differences in lipid profiles of aqueous humor (AH) in patients with open-angle glaucoma (OAG). MATERIALS AND METHODS The lipidomic profile of 10 samples of AH of patients with OAG and 10 controls was analyzed. Patients with a history of anterior segment surgery, anterior segment pathology, or intraocular injections were excluded. Topical ocular medications w...

Purpose To report two patients with giant retinal tear (GRT) associated retinal detachment in the setting of baseball trauma. Observations Two patients presented with retinal detachment associated with GRT following blunt trauma with a baseball. The first was a superotemporal GRT detachment treated with scleral buckling, pars plana vitrectomy, endolaser, and silicone oil injection. He subsequ...

AIM To demonstrate the influence of intraocular fluid-air exchange on retinal ganglion cell activity. METHODS In two cats lensectomy and vitrectomy were performed in a two-step approach 2 weeks prior to recording experiments. To measure retinal activity, up to two fiber microelectrodes were inserted via a scleral port. Precise micromanipulator positioning of the electrodes' tips onto the inne...

Neonatal aphakia is associated with retardation of the axial elongation of the neonatal eye. In contrast, form deprivation increases axial elongation, an effect that has been associated with decreased retinal dopamine metabolism. The present investigation was conducted to test the hypothesis that neonatal aphakia induces an effect on the levels of retinal dopamine opposite to form deprivation. ...

AIMS To assess the outcome and complications of patients with advanced retinopathy of prematurity (ROP). METHODS All patients with eyes achieving stage 4 or 5 retinopathy of prematurity were reviewed. Twenty one eyes were diagnosed during ROP screening in maternity hospitals and 10 eyes were of infants transferred for treatment. RESULTS Thirty one eyes of 17 patients were included. Thirteen...

Quantitative methods to measure ocular glucose consumption in vivo, which is dominated by the retina, could provide considerable information about retinal metabolism in healthy and disease states. Eyes that are totally ischemic for at least 4 hr retain good retinal histopathologic features if treated with vitreoperfusion. In such cases, the vitreoperfusion fluid essentially is the only extraret...

Purpose The purpose of this study is to evaluate effects of vitrectomy (PPV) and lens extraction with intraocular lens implantation (PE/IOL) on molecular oxygen (pO2) distribution, aqueous humor antioxidant-oxidant balance, aqueous humor dynamics, and histopathologic changes in the trabecular meshwork (TM) in the older macaque monkey. Methods Six rhesus monkeys underwent PPV followed by PE/IO...