recently, extensive efforts have been made to understand the rate of energy expenditure and the weight gain associated with atypical antipsychotic treatment, including identification of markers of obesity risk. in recent years, leptin, an adipocyte hormone, has gained significant interest in psychiatric disorders. s100b has been considered as a surrogate marker for astrocyte-specific damage in ...

conclusions the findings suggest that low levels of leptin may be a contributory factor for malnutrition in hd patients. further studies are required to ascertain the significance of leptin levels in relation to nutritional factors in hemodialysis patients. patients and methods this analytical descriptive study included 45 hemodialysis patients and 40 healthy subjects. biochemical parameters an...

objective: serum leptin concentration reflects the body fat mass. there is controversial reports about the insulin effect on serum leptin concentration. we wanted to examine the effect of insulin therapy on serum leptin in children with new onset type i diabetes. materials and methods: this was a cross-sectional study in children's medical center on 34 children who had new onset type i dia...

The study aimed to investigate the effect of in ovo (IO) leptin injection on yolk sac concentration, embryo development, blood lipid metabolism, and biochemical parameters broiler chicks during early post-hatching period. Hatching eggs were weighed placed an incubator with 100 eggs/4 replications/group. groups were: non-injected group (C); 3 injected μl phosphate buffer solution (PBS); 0.5 (L0....

Obesity has been identified as a serious health concern in domestic cats. Feline mammary cancer (FMC) is also concern, it highly prevalent and aggressive. Considering the connection between obesity breast cancer, worthwhile to investigate potential obesity–cancer relationship FMC. This review investigated association adipokines other obesity-associated molecules FMC, with aim of identifying gap...

background: the relationship between metabolism and reproduction has been always considered as an important topic in female endocrinology. it seems that leptin is one of the involved factors in infertility. leptin, in addition to regulating body weight plays an important role in regulation of endocrine, reproductive and immune systems. the aim of this stduy is to compare serum and follicular fl...

Obesity is a chronic disease that shows the most serious global health problems .It relates to the body fat .Obesity is caused by an imbalance between energy intake and expenditure, this balance is regulated by genetic and environmental interactions. Obesity, which is a risk factor for chronic diseases, has become epidemic in the developed countries. Resistance to Leptin hormone is one of the m...

NONALCOHOLIC FATTY LIVER DISEASE (NAFLD) encompasses a spectrum ranging from simple steatosis to steatohepatitis (NASH), increasing fibrosis and eventually, cirrhosis (22). Importantly, NASH accompanied by fibrosis and severe inflammation is the most relevant predictor for disease progression to cirrhosis and hepatocellular carcinoma (21). NAFLD is tightly associated with obesity, insulin resis...

Background The aim of this study was to evaluate leptin serum levels in patients with major beta thalassemia which was also associated with their ferritin serum levels. Materials and Methods This case-control study was performed on 90 children -6 months to 16 years old, in Zabol, Amir- al- Momenin Hospital. Patients were divided in two groups and were matched in age and sex. All Children w...

What is hunger? How do we know how much to eat? And what happens if not eat enough? To survive, the human body must have energy reserves available in form of fat. Using a hormone called leptin, fat tissue regularly sends messages brain about body’s reserves. When receives lot it tells body, “you are full, stop eating.” In certain situations, like obesity and pregnancy, less sensitive leptin—so ...