Background: Hepatitis C virus (HCV) is a main public health problem causing chronic liver infection and subsequently liver cirrhosis and lethal hepatocellular carcinoma (HCC). Vaccination based on HCV capsid proteins has attracted a special interest for prevention of viral infections. The core protein is a basic and evolutionary most conserved protein, which regulates the cellular processes rel...

multiple sclerosis (ms) is a chronic inflammatory disease that leads to degeneration of the brain and spinal tissue. imbalances of cd4+ t cells including thelper1 (th1)/thelper2 (th2) and thelper17 (th17)/tregulatory (treg), their secreted cytokines and gene expressions, are important aspects of in immunopathogenesis of ms. vitamin a and its metabolites can regulate the immune system and appear...

Facial expressions are the most powerful and direct means of presenting human emotions and feelings and offer a window into a persons’ state of mind. In recent years, the study of facial expression and recognition has gained prominence; as industry and services are keen on expanding on the potential advantages of facial recognition technology. As machine vision and artificial intelligence advan...

Background: Toll-like receptors (TLRs) play a crucial role in early host defense against invading pathogens. Recognition of some bacterial pathogen associated molecular patterns (PAMPs) is mediated by TLR2, 4 and 5 while TLR3 distinguishes double stranded RNA. Interactions between the immune system and female reproductive system have important consequences for fertility and reproductive health....

Bacterial expression systems provide economic and logistic advantages in manufacturing proteins for human therapeutic purposes. However, most such proteins accumulate in insoluble biologicaIIy inactive form when overexpressed in bacterial cells. This is the case while attempting to produce recombinant human granulocyte-macrophage colony stimulating factor (hGM-CSF) in E. coli. In this repor...