The effect of adding 6% dextran to a lignocaine solution containing adrenaline was studied in 27 neurosurgical patients during modified neuroleptanaesthesia. Before trepanation they received infiltration anaesthesia of the scalp at the site of the proposed operation. For a period of 1 h following injection plasma concentrations of adrenaline were measured by high pressure liquid chromatography ...

Current treatment protocol for postoperative pain is to infuse anesthetic solution around nerves or into the epidural space. This clinical practice is beset by the short duration of the anesthetic effect unless the infusion is continuous. Continuous infusion, however, requires hospitalization of the patients, thereby increasing medical costs. In addition, it also causes systemic accumulation of...

Background: Visceral and shoulder painare among the most frequent reported pain after laparoscopic cholecystectomy (LC). Objectives: To investigate effectiveness clinical value of rectal indomecthacin and  intraperitoneal lidocaine  for treating cholecystectomy. Patients methods: In Qena university hospital, this prospective randomized comparative study was conducted, 80 patients were schedul...

INTRODUCTION In maxillofacial surgery, the simplest procedure that we perform is dental extraction. However, this simple procedure is challenged by the patient's poor medical condition. We generally use local anesthesia in combination with adrenaline; however, as we come across patients with diabetes mellitus and cardiovascular diseases who seek dental extraction, we need to be doubly cautious ...

solution, which prompted an immediate discharge from the cutaneous granular glands. The skin was then cut into small pieces and cultured in a nutrient/salts medium in a manner similar to that described by Baily (1971). One of the amino acids in the medium was replaced by the 3H-labelled amino acid. The skin cultures were incubated for up to 7 days at 28°C. After 3 and 7 days, samples of skin we...

Twelve healthy young volunteers were studied before and during intravenous administration of lidocaine at a dose rate of 2 or 4 mg/min. Five additional volunteers, who did not receive lidocaine solution but were given the same amount of physiological saline, were studied in the same manner. Heart rate, cardiac output, mean arterial blood pressure, mean right atrial blood pressure, estimated hep...

BACKGROUND The effect of vasoconstrictors in prolonged cardiopulmonary resuscitation (CPR) has not been fully clarified. OBJECTIVES To evaluate adrenaline and vasopressin pressure effect, and observe the return of spontaneous circulation (ROSC). METHODS A prospective, randomized, blinded, and placebo-controlled study. After seven minutes of untreated ventricular fibrillation, pigs received ...