نتایج جستجو برای: like fragments
تعداد نتایج: 705432 فیلتر نتایج به سال:
In mass-conservative homogeneous fragmentations, sizes of the fragments decrease at asymptotic exponential rates. Like in branching processes, two situations occur: either the number of such fragments is exponentially growing the rate is effective -, or the probability of presence of such fragments is exponentially decreasing [3],[12]. In a recent paper [18], N. Krell considers fragments whose ...
The conversion of kinetic energy into target-like fragment excitation and orbital angular momentum into fragment spin has been studied in the reaction 333 MeV Si with ' 'Ta. The light charged particles were detected in a small, highly segmented, 4m phoswich detector system placed in the spin spectrometer, a 4m NaI array which served as a neutron and gamma detector. Multiplicities of light charg...
Diese Dissertation wurde selbstständig, ohne unerlaubte Hilfsmittel erarbeitet. Rothenfusser S, Hopfner KP (2009). " The regulatory domain of the RIG-I family ATPase LGP2 senses double-stranded RNA.
CD44 is a receptor for hyaluronan and mediates signaling that regulates complex cell behavior including cancer cell migration and invasion. Shedding of the extracellular portion of CD44 is the last step in the regulation of the molecule-releasing interaction between the ligand and cell. However, highly glycosylated forms of CD44 have hampered the identification of the exact cleavage sites for s...
The incretin hormone glucagon-like peptide 1 (GLP-1) promotes glucose homeostasis and enhances β-cell function. GLP-1 receptor agonists (GLP-1 RAs) and dipeptidyl peptidase-4 (DPP-4) inhibitors, which inhibit the physiological inactivation of endogenous GLP-1, are used for the treatment of type 2 diabetes. Using the Metabochip, we identified three novel genetic loci with large effects (30-40%) ...
The fibrillation and deposition of amyloid-β (Aβ) peptides in human brains are pathologically linked to Alzheimer's disease (AD). Development of different inhibitors (peptides, organic molecules, and nanoparticles) to prevent Aβ aggregation becomes a promising therapeutic strategy for AD treatment. We recently propose a "like-interacts-like" design principle to computationally design/screen and...
Mammary sclerosing lobular hyperplasia (SLH) is a rare, benign, fibroproliferative tumour-like lesion of adolescent and young women often of African-American heritage. Fine-needle aspiration cytology of mammary SLH shows characteristic features that include an absence of stromal fragments. We report a 45-year-old woman who presented with a gradually enlarging, painless, mobile 4-cm tumour in he...
The contribution of polymorphonuclear neutrophils (PMN) to host defense and natural immunity extends well beyond their traditional role as professional phagocytes. In this study, we demonstrate that upon stimulation with proinflammatory stimuli, human PMN release enzymatic activities that, in vitro, generate bioactive angiostatin fragments from purified plasminogen. We also provide evidence tha...
Effect of ADP and ionic strength on the kinetic and motile properties of recombinant mouse myosin V.
Mouse myosin V is a two-headed unconventional myosin with an extended neck that binds six calmodulins. Double-headed (heavy meromyosin-like) and single-headed (subfragment 1-like) fragments of mouse myosin V were expressed in Sf9 cells, and intact myosin V was purified from mouse brain. The actin-activated MgATPase of the tissue-purified myosin V, and its expressed fragments had a high V(max) a...
Anaplasma marginale genomic DNA was tested for the presence of repetitive extragenic palindromic (REP) and enterobacterial repetitive intergenic consensus (ERIC)-like sequences in order to evaluate the genetic diversity of multiple A. marginale isolates. A. marginale isolates were obtained from cattle of six different states of Brazil, from the US and an Anaplasma centrale strain was obtained f...
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