The entry of leukocytes into tissues requires well-coordinated interactions between the immune cells and endothelial cells which form the inner lining of blood vessels. The molecular basis for recognition, capture, and adhesion of leukocytes to the endothelial apical surface is well studied. This review will focus on recent advances in our understanding of events following the firm interaction ...

Irrigation canals are generally made through porous soil formations, since the is loose media – a huge amount of canal water lost to conveyance losses. The situation becomes direr when these losses result in non-beneficial Sindh province Pakistan has more than 70% saline groundwater, such areas not only become unusable but also creates management problems. Perhaps cost-effective way address lin...

The objective of these analyses was to assess the penetration of tigecycline into colon wall tissue and epithelial lining fluid (ELF). The analyses included data from subjects without infection (phase 1) and patients with intra-abdominal infections (phase 2/3). Steady-state serum samples were collected from all subjects/patients (n = 577), while colon wall specimens (n = 23) and ELF specimens (...

BACKGROUND To study CT and MR findings in xanthogranulomatous cholecystitis (XGC). MATERIAL/METHODS Retrospective analysis of 30 histopathologically confirmed cases of XGC. Seventeen patients underwent CECT and 13 underwent MRI. The following features were studied - wall thickness, intramural nodules, pericholecystic stranding, wall thickness, THAD, fat in gallbladder wall, cholelithiasis, in...

Tunneling can compromise the safety and serviceability of existing buried infrastructure because settlements, crack openings, dislocations, material strains. A continuum-based soil-structure interaction model, implementing an equivalent Timoshenko beam, is used to evaluate excavation-induced settlements longitudinal deformations tunnels pipelines. Both single twin tunneling scenarios are examin...

We investigated the role of c-Kit and the membrane-bound ligand (mbKitL) in endothelial progenitor cell (EPC) recruitment by microvascular endothelial cells (ECs). We demonstrated that inflammatory activation induced the expression of the mbKitL on ECs both in vitro and in vivo, and that recruitment of EPCs depended on c-Kit/mbKitL interaction. Depletion of endogenous c-Kit or inhibition of c-K...