We have examined, by analyzing thin (15-20 nm) serial sections, whether coated pits involved in adsorptive pinocytosis in cultured fibroblasts give rise to free coated vesicles or represent permanently surface-associated structures from the neck of which uncoated receptosomes pinch off and carry ligand into the cell. Human skin fibroblasts and mouse L-929 fibroblasts were incubated with cationi...

Several different endocytic pathways have been proposed to function in mammalian cells. Clathrin-coated pits are well defined, but the identity, mechanism and function of alternative pathways have been controversial. Here we apply universal chemical labelling of plasma membrane proteins to define all primary endocytic vesicles, and labelling of specific proteins with a reducible SNAP-tag substr...

Triple junctions (TJs) are the lines where three grains or grain boundaries meet and become increasingly important in nanocrystalline materials where they have a high areal number density and occupy a significant fraction of the total volume of the material. Surface pits are associated with TJs, just as surface grooves are associated with grain boundaries, and these pits may have particularly d...

LiDAR canopy height models (CHMs) can exhibit unnatural looking holes or pits, i.e., pixels with a much lower digital number than their immediate neighbors. These artifacts may be caused by a combination of factors, from data acquisition to post-processing, that not only result in a noisy appearance to the CHM but may also limit semi-automated tree-crown delineation and lead to errors in biomas...

Lip tracking has played a significant role in a lip reading system. In this paper, we present a local region based approach to lip tracking, which consists of two phases: (i) lip contour extraction for the first lip frame, and followed by (ii) lip tracking in the subsequent lip frames. Initially, we construct a localized color active color model provided that the foreground and background regio...

The unicellular conifer tracheid should have greater flow resistance per length (resistivity) than the multicellular angiosperm vessel, because its high-resistance end-walls are closer together. However, tracheids and vessels had comparable resistivities for the same diameter, despite tracheids being over 10 times shorter. End-wall pits of tracheids averaged 59 times lower flow resistance on an...

Gorlin-Goltz syndrome (GGS) among Indians is rarely reported. Since 1960, only 38 cases having 48 patients of have been identified in the Indian population. It crucial to diagnose this illness early because it can be connected a malignant lesion like fibrosarcoma, leiomyosarcoma or rhabdomyosarcoma. The four case series were and treated our department between 2019 2023. average patient age was ...

The objective was to explore quantitative methods for the measurement of lip mobility and lip force and to relate these to qualitative assessments of lip function. Fifty healthy adults (mean age 45 years) and 23 adults with diagnoses affecting the facial muscles (mean age 37 years) participated in the study. Diagnoses were Möbius syndrome (n=5), Facioscapulohumeral muscular dystrophy (n=6) and ...

Corrosion surface damage in the form of pitting and micro-cracks is observed in many metals. Cracks usually initiate from the pits and grow under cyclic stresses and eventually lead to material failure. An image analysis based on wavelet transforms and fractals was used to study the corrosion morphology of nickel aluminum bronze metal under varying corrosion conditions and applied stresses. Ima...

introduction: advanced lip carcinomas can invade adjacent structures. performing surgery for these cancers will lead to defects in this anatomically and functionally important area and will cause post-op difficulties such as drooling, speech alterations and aesthetic considerations, if not properly managed. case report: in this study, we will introduce a radial forearm free flap with palmaris l...