Current experimental research on albino rats has studied the effect of salmonellae and T2 toxin on indices of lipid peroxidation (LPO) and antioxidant protection. Joint effect of bacteria and toxicant, especially in a dose of 560.0μg/kg, was characterized by a more evident increase of integral index of blood and liver LPO – malonic dialdehyde (MDA) by 1.7 and 4.4 times, respectively, and also b...

A single dose of CCl4 (1 ml/kg body weight, po in corn oil) increased the levels of SGOT (serum glutamate oxaloacetate transaminase), SGPT (serum glutamate pyruvate transaminase), LDH (lactate dehydrogenase), glutathione-S-transferase and depletion in reduced glutathione, glutathione peroxidase and glutathione reductase. It also caused enhancement in the levels of lipid peroxidation (LPO) and D...

Abstract Desvenlafaxine succinate (DVS) inhibits serotonin reuptake selectively and is approved for major depressive disorders. This research investigated influence of DVS on modulating brain monoamine oxidative stress in mice. The antiepileptic potential (10, 20, or 30 mg/kg/i.p.) pentylenetetrazole (PTZ; 85 mg/kg) with i.p. route administration, strychnine (STR; 75 route, pilocarpine (400 s.c...

This work sought to ascertain survival and possible changes in levels of glycogen, triglycerides, total lipids, cholesterol, protein, and lipid peroxidation in gills, liver, and muscle of bullfrog tadpoles (Lithobates catesbeianus) exposed to low concentrations of atrazine (2.5 μg L(-1)), glyphosate (18 μg L(-1)), and quinclorac (0.025 μg L(-1)) at laboratorial conditions. Tadpoles showed a red...

Melatonin (MT) (N-acetyl-5-methoxytryptamine) is a lipophilic and hydrophilic indoleamine with various physiologic functions MT presents in all cells and tissues and distributes in all cell compartments. Liver is the only organ of circulating MT metabolism. The roles of MT in various liver pathologies have been extensively studied, and it is believed that oxidative stress (OS) and lipid peroxid...

Study on the chronic effects of an organophosphate, chlorpyrifos inducing oxidative stress in freshwater culturable carp, Ctenopharyngodon idellus has been made on exposure to sub-lethal concentration (1.41μg/L and 2.44μg/L) of the pesticide for 15, 30 and 60 days. Antioxidants viz. catalase (CAT), superoxide dismutase (SOD), reduced glutathione (GSH), glutathione-s-transferase (GST) and lipid ...

BACKGROUND Curcumin (Cur), an active ingredient of turmeric is known to have multiple activities, including an antioxidant property and has been suggested to be useful in treatment of several neurological diseases. OBJECTIVE To investigate the neuroprotective effects of Cur to mitigate the effect of the Fluoride (F) induced neurotoxicity in mice brain using the histological and the biochemica...

E-mail: [email protected] The experiment was performed on white rats and content of malondialdehyde and conjugated dienes in the retina and blood plasma in the condition of streptozotocineinduced diabetes development and quercetine and lipoate application was studied. In such conditions, the use of drugs studied significantly prevented an increase in temporary products of lipid peroxidation ...

The aim of this study was to evaluate the protective effect of catechin and quercetin in sodium benzoate- (SB-) induced oxidative stress in human erythrocytes in vitro. For this, the effects of SB (6.25, 12.5, 25, 50, and 100 μg/mL), catechin (10 μM), and quercetin (10 μM) on lipid peroxidation (LPO) and the activities of SOD, CAT, GPx, and GST were studied. Significantly higher LPO and lower a...

Insulin-dependent diabetes mellitus (IDDM) is a metabolic condition that induces blood glucose levels to rise due insulin deficiency and the formation of reactive oxygen species (ROS). The purpose this study assess how efficient antioxidant extracts Tribulus terrestris (TT) metformin (MET) are in reducing oxidative stress histopathology produced by streptozotocin rat hepatocytes. 36 male rats w...