Abstract Sequencing of cell-free DNA in the blood cancer patients (liquid biopsy) provides attractive opportunities for early diagnosis, assessment treatment response, and minimally invasive disease monitoring. To unlock liquid biopsy analysis pediatric tumors with few genetic aberrations, we introduce an integrated genetic/epigenetic method demonstrate its utility on 241 deep whole-genome sequ...

Oral health is a key indicator of overall health, well being and quality life. Mouth ulcers are small sores that form on your lips, gums, inner cheeks, toung or palate. They painful can be extremely uncomfortable make it difficult for some people to eat, drink, brush their teeth. triggered by several different factors including minor injuries, hormonal changes, emotional stress, vitamin deficie...

Chinese liquorice (Glycyrrhiza uralensis Fisch. ex DC.) is widely used in the food industry and as a medicine. Like other legumes, G. forms symbiotic nodules. However, structural organization of nodules poorly understood. In this study, we analyzed histological ultrastructural dynamics tubulin cytoskeleton various cells from different zones indeterminate formed by two strains Mesorhizobium sp. ...

This study evaluated the stability characteristics of oil-in-water emulsions prepared using purified glycyrrhizin (PG) or a non-purified glycyrrhizin-rich extract from liquorice root (LRE) at equivalent concentrations (0.01−0.1%, w/w). PG-stabilized were sensitive to acidic pH (< 5), NaCl addition (≥ 50 mM), and freeze-thaw cycles. Consequently, they showed signs droplet coalescence upon storag...

Diseases in human life are one of the huddle to live life, which consist chronic and acute diseases. Cough is a common respiratory symptom that can have significant impact on quality life. Polyherbal formulations been used for centuries traditional medicine treat coughs other ailments. In this study, we prepared polyherbal cough syrup using combination medicinal plants act as natural ingredient...

Background: Although both the root and rhizome of Glycyrrhiza inflata have been used as medicinal material, sales volume price its are much higher than rhizomes. Limiting growth liquorice rhizomes while improving yield quality has become an important problem. Methods: Two irrigation patterns (surface drip subsurface irrigation, i.e. DI SDI) three levels (40%-50%, 60%-70% 80%-90% maximum soil wa...