Among those with moderate-to-advanced chronic kidney disease, the relationship between blood pressure (BP) and cardiovascular disease seems U shaped but is loglinear in apparently healthy adults. The SHARP (Study of Heart and Renal Protection) randomized 9270 patients with chronic kidney disease to ezetimibe/simvastatin versus matching placebo and measured BP at each follow-up visit. Cox regres...

In randomized clinical trials where the effects of post-randomization factors are of interest, the standard regression analyses are biased due to unmeasured confounding. The instrumental variables (IV; Angrist et al., 1996) and G-estimation procedures under structural nested mean models (SNMMs; Robins, 1994) allow one to make valid inference even if unmeasured confounding is present. Two IV app...

A theoretical relationship between isolation by distance or spatial genetic structure (SGS) and seed and pollen dispersal is tested using extensive spatial-temporal simulations. Although for animals Wright's neighbourhood size N(e) = 4pisigma(2)(t) has been ascertained also, where sigma(2)(t) is the axial variance of distances between parents and offspring, and it was recently confirmed that N(...

This paper represents the first attempt to develop a set of loglinear models that synthesize gravity models of interregional mobility and loglinear models of occupational mobility. The development of the model is progressed from a simple two-way mobility table analysis to a three-way analysis that controls for one aspect of mobility while investigating another and eventually to a four-way analy...

Tendo em vista o grau do impacto que doenças psicológicas, como burnout e depressão, gera profissionais trabalham no ambiente prisional. O objetivo desse estudo consiste analisar a influência das variáveis sociodemográficas na relação entre depressão agentes prisionais. Para atingir da pesquisa, este adotou uma abordagem quantitativa de natureza descritiva, qual 189 prisionais responderam ao Qu...

Bikeshare provides important first mile–last mile, commuting, circulation, and sightseeing options in many cities. can also be healthy convenient for users. Throughout the year, holidays occur that change typical bikeshare activity patterns. Existing literature shows mixed results relating to ridership impacts of holidays: some research these days may result higher ridership, whereas others sho...

Abstract Heuristic rules are appropriate, if a decision maker wants to set the price of new product or product, whose past variation is low, and budget limitations prevent use marketing experiments customer surveys. Whereas such not guaranteed provide optimal price, generated profits should be as close possible their values. We investigate eleven pricing that do require knows response function ...

Population growth and climate change require efficient use of water resources per unit area. In this study, the relationships between irrigation systems, land sizes crop patterns farmers in coastal areas were determined to provide useful information for better agricultural management. A survey study was conducted with 170 using stratified sampling method. The relationship varieties, methods by ...

In regression analysis of count data, independent variables are often modeled by their linear effects under the assumption of log-linearity. In reality, the validity of such an assumption is rarely tested, and its use is at times unjustifiable. A lack-of-fit test is proposed for the adequacy of a postulated functional form of an independent variable within the framework of semiparametric Poisso...