نتایج جستجو برای: lomefloxacin
تعداد نتایج: 180 فیلتر نتایج به سال:
Vernal Shield ulcer is a rare sight threatening corneal manifestation of vernal keratoconjunctivitis. This study is designed to report management of a refractory shield ulcer that did not respond to variety of medications but healed in 1 week after surgical debridement of ulcer base. A 12-year old Omani boy with H/O vernal conjunctivitis since 5 years on ketotifen eye drops presented with a shi...
Grepafloxacin (GPFX) is a new quinolone antibiotic (NQ) which is highly distributed to the lung and other tissues. In the present study, to characterize the distribution mechanism of GPFX to the lung, the uptake of GPFX by isolated rat lung cells was examined in vitro. GPFX was rapidly taken up by the cells, and the uptake reached a steady-state within 5 min. The cell-to-medium concentration ra...
This paper presents an analytical method which allows the determination of 11 quinolone antibiotic residue in bovine liver: pipemidic acid, ofloxacin, ciprofloxacin, danofloxacin, lomefloxacin, enrofloxacin, sarafloxacin, cinoxacin, oxolinic acid, nalidixic acid, and flumequine. The procedure involves a rapid and efficient pretreatment by Bond Elut QuEChERS kits. The homogenized liver sample wa...
OBJECTIVE To survey cases of fluoroquinolone-associated adverse events that included peripheral nervous system (PNS) symptoms posted on Internet Web sites. METHODS Cases were obtained with the assistance of members of Web sites formed by people sustaining fluoroquinolone-related events. Information obtained met the standards of MedWatch, and each reported case was assessed using the Naranjo p...
The antibacterial activities and target inhibition of 15 quinolones against grlA and gyrA mutant strains were studied. The strains were obtained from wild-type Staphylococcus aureus MS5935 by selection with norfloxacin and nadifloxacin, respectively. The antibacterial activities of most quinolones against both mutant strains were lower than those against the wild-type strain. The ratios of MICs...
BACKGROUND The rapid development of effective medical countermeasures against potential biological threat agents is vital. Repurposing existing drugs that may have unanticipated activities as potential countermeasures is one way to meet this important goal, since currently approved drugs already have well-established safety and pharmacokinetic profiles in patients, as well as manufacturing and ...
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