The striking and unique structural feature of the T cell receptor (TCR) beta chain is the bulky solvent-exposed FG loop on the Cbeta domain, the size of almost half an immunoglobulin domain. The location and size of this loop suggested immediately that it could be a crucial structural link between the invariant CD3 subunits and antigen-recognizing alpha/beta chains during TCR signaling. However...

This paper presents an implementation of open loop and closed loop control of Quadratic boost converter using PID controller.  Quadratic boost converter consists of boost converter and fly back converter driven by a single switch. Quadratic boost converter QBC is designed especially for regulating the DC interface between various micro sources and dc-ac inverter to electricity grid. Quadratic b...

in this paper, firstly by using a mixed linear programming a new model of locating facilities with limited capacity is presented to design a closed-loop supply chain in a multi-product and multi-period mode. then, using a robust optimization approach, the proposed model decreases in non-deterministic expansion. the results show that the proposed model can handle facility capacity in a closed lo...

The ATP binding cassette (ABC) proteins make up a large superfamily with members coming from all kingdoms. The functional form of the ABC protein nucleotide binding domain (NBD) is dimeric with ATP binding sites shared between subunits. The NBD is defined by six motifs: the Walker A, Q-loop, Signature, Walker-B, D-loop, and H-loop. The D-loop contains a conserved aspartate whose function is not...

Pit2 is the human receptor for amphotropic murine leukemia virus (A-MuLV); the related human protein Pit1 does not support A-MuLV entry. Interestingly, chimeric proteins in which either the N-terminal or the C-terminal part of Pit2 was replaced by the Pit1 sequence all retained A-MuLV receptor function. A possible interpretation of these observations is that Pit1 harbors sequences which can spe...

During active behaviours like running, swimming, whisking or sniffing, motor actions shape sensory input and sensory percepts guide future motor commands. Ongoing cycles of sensory and motor processing constitute a closed-loop feedback system which is central to motor control and, it has been argued, for perceptual processes. This closed-loop feedback is mediated by brainwide neural circuits bu...

this paper presents a gain scheduled autopilot for pitch channel of a flying vehicle. the selected method is based on polynomial fuzzy systems. the method does not involve linearization about operating point. first the polynomial fuzzy model of pitch channel of the flight body is derived. next, using polynomial fuzzy system methodology the controller is design such that the outputs of the nonli...

control of three phase inverters has been an important issue in recent years. this paper proposes active disturbance rejection control (adrc) scheme for controlling three phase inverters. the main advantage of adrc that motivated us for using this controller for inverter is that it is model independent.  this controller is used in a double loop structure including an inner current loop and oute...

 ABSTRACT Background: The loop colostomy is one of the most popular techniques used as a protective maneuver for a distal anastomosis and/or temporary fecal diversion. We are introducing the use of a full thickness skin bridge under the large bowel instead of a glass rod which alleviates problems such as protrusion of the large bowel, retraction of the bowel into the abdomen after removing the ...

Introduction: Regarding the anatomic variety in the anterior mandible it is necessary to obtain adequate information about the vital structures in this area to protect them in dental surgeries and preventing injuries that might occur afterwards. The aim of this study is to describe anatomic characteristics of mental foramen and anterior loop on CBCT images.  Materials and Methods: On CBCT imag...