Although granulocyte transfusion is a logical, therapeutic option for neutropenic patients with refractory infections, significant technical barriers have prevented its widespread use. A novel phagocyte transfusion strategy has been developed based on activation of a human myeloid cell line HL-60. To further define the potential for HL-60 cells to recapitulate white cell transfusions, a shorten...

Hodgkin lymphoma (HL) is an uncommon malignancy involving lymph nodes and lymphatic system. Due to the progress of the treatment, HL becomes a potentially curable disease. International Prognostic Index (IPI) was defined as the number of adverse prognostic factors presented at diagnosis. This report aims to assess the predictive power of the IPI for HL patients. On the basis of the retrospectiv...

Signaling through the IL-1-receptor type 1 (IL-1R1), IL-1 is required for initiation and maintenance of diverse activities of the immune system. A second receptor, IL-1R2, blocks IL-1 signal transduction. We studied expression of IL-1beta, IL-1R1, and IL-1R2 in 17 Hodgkin lymphomas (HL) by in situ hybridization (ISH). IL-1beta expressing cells, morphologically consistent with endothelial cells ...

The mechanism by which ethinyl estradiol (EE) decreases the concentration of lipids in the d< 1.019 g/ml fraction (/J-very low density lipoprotein [0-VLDL]) of homozygous Watanabe heritable hyperlipidemic (WHHL) rabbits was studied. Treatment with EE increased the activity of hepatic lipase (HL) twofold to threefold in postheparin plasma and in liver biopsies. Postheparin plasma and adipose tis...

Support vector regression (SVR) has been widely used to reduce the high computational cost of computer simulation. SVR assumes input parameters have equal sample sizes, but unequal sizes are often encountered in engineering practices. To solve this issue, a new prediction approach based on SVR, namely as high-low level (HL-SVR) is proposed for data modeling paper. The consists low-level models ...

a new approach for propulsion system layout that increases power and enhances the efficiency of submarine propulsion system is proposed.using our method,the efficiency and power of the system enhances without increasing volume and weight. this layout improves the performance compared to the usual layout, which employs double-armature motors in cruise speed where efficiency is more critical. thi...

systems thinking is not a new concept to health system strengthening; however, one question remains unanswered: how policy-makers, system designers and consultants with a system thinking philosophy should act (have acted) as potential change agents in actually gaining opportunities to introduce systems thinking? development of comprehensive multi-year plans (cmyps) for immunization system is on...

objective: sufficient intakes of docosahexaenoic acid (dha) via breast milk are required for optimizing visual and neural development at early stages of life. little or no information is available on dha intakes and levels found in breast milk in iranian women and surrounding regions. in this study we measure the dha in the breast milk of lactating iranian women from low and high – fish-eating ...