BACKGROUND After introducing the specific thrombin inhibitor recombinant hirudin (r-hirudin) into clinical practice in cases of heparin-induced thrombocytopenia (HIT, type II) the possibility of its use as an anticoagulant during haemodialysis treatment in HIT II patients is being discussed more frequently. On the one hand, the efficient, safe and routine use of r-hirudin during haemodialyses, ...

The efficacy of combination therapy (antiretroviral therapy--ARV) is demonstrated by the high rates of viral suppression achieved in most treated HIV patients. Whereas contemporary treatments may continuously suppress HIV replication, they do not eliminate the latent reservoir, which can reactivate HIV infection if ARV is discontinued. The persistence of HIV proviral DNA and infectious viruses ...

Normal reflection from a fractured reservoir is analyzed using frequency-dependent seismic attributes. Processing of 3D low-frequency seismic data from a West-Siberian reservoir produced an accurate delineation of the fractured hydrocarbon-bearing zones. P-wave propagation, reflection and transmission at an impermeable interface between elastic and dual-porosity poroelastic media is investigate...

Forced displacement of oil by polymer flooding in oil reservoir is one of the effective methods of enhanced (tertiary) oil recovery. A classical model of this process within Hele-Shaw approximation involves three-layer fluid in a Hele-Shaw cell having a variable viscosity fluid in the intermediate layer between oil and water. The goal here is to find an optimal viscosity profile of the intermed...

We employ the PhaseChip, a (poly)dimethylsiloxane (PDMS) microfluidic device, for statistical studies of protein crystal nucleation. The PhaseChip is designed to decouple nucleation and growth of protein crystals and so improve their yield and quality. Two layers of fluidic channels containing salt reservoirs and nanoliter-sized wells for protein drops in oil are separated by a thin PDMS membra...

Development of borehole geophysics has recently focused on reservoir characterization. Within this effort, extensive full waveform acoustic surveys have demonstrated a correlation between the occurance of open fractures and attenuation of Stoneley waves. A relationship is obtained here between fracture permeability and attenuation of Stoneley waves, on the basis of a physical mechanism. This me...

Compressional waves in heterogeneous permeable media suffer attenuation fiom both scattering and induced pore scale flow of the viscous saturating fluid. Stochastic medium theories are used to describe scattering on multiple length scales, and are validated by numerical examples using a dual length scale sedimentary sequence taken from a producing oil reservoir. The highly variable permeability...

We employ the PhaseChip, a (poly)dimethylsiloxane (PDMS) microfluidic device, for statistical studies of protein crystal nucleation. The PhaseChip is designed to decouple nucleation and growth of protein crystals and so improve their yield and quality. Two layers of fluidic channels containing salt reservoirs and nanoliter-sized wells for protein drops in oil are separated by a thin PDMS membra...

Summary Fault slip induced by fluid perturbation in shale formations may only lead to as sparse seismicity. However, fault strongly impact the integrity of that serve caprocks for geological reservoirs holding buoyant fluids such CO2, natural gas, or hydrogen. A better understanding reactivation processes and seismic triggering process is therefore critical reservoir monitoring stability. Here ...