نتایج جستجو برای: low phosphate

تعداد نتایج: 1293212  

2014
Daniel Gonzalez Magali Richez Celine Bergonzi Eric Chabriere Mikael Elias

Phosphate limitation is an important environmental stress that affects the metabolism of various organisms and, in particular, can trigger the virulence of numerous bacterial pathogens. Clostridium perfringens, a human pathogen, is one of the most common causes of enteritis necroticans, gas gangrene and food poisoning. Here, we focused on the high affinity phosphate-binding protein (PBP-1) of a...

Journal: :Cancer research 1985
M Kanje J Deinum M Wallin P Ekström A Edström B Hartley-Asp

Estramustine phosphate (0.01 to 0.5 mM), an estradiol mustard derivative used in the therapy of prostatic carcinoma, inhibited the assembly of brain microtubules proteins in vitro and disassembled preformed microtubules. In the presence of estramustine phosphate, the minimum microtubule-protein concentration sufficient for the assembly of microtubules was increased. Low concentrations of taxol ...

Journal: :Journal of nutritional science and vitaminology 1983
F Shimura M Watanabe J Shimura N Hosoya

The effect of pyridoxal 5'-phosphate on the 1,25-dihydroxyvitamin D3 receptor system has been studied by using pig intestinal chromatin. Pyridoxal 5'-phosphate did not affect the binding of 1,25-dihydroxyvitamin D3 to its receptor extracted from chromatin with hypertonic KCl, although in the presence of pyridoxal 5'-phosphate 1,25-dihydroxyvitamin D3-receptor complexes were not readily precipit...

Journal: :Archives of biochemistry and biophysics 2006
Júlio C Borges José H Pereira Igor B Vasconcelos Giovanni C dos Santos Johnny R Olivieri Carlos H I Ramos Mário S Palma Luiz A Basso Diógenes S Santos Walter F de Azevedo

The 5-enolpyruvylshikimate-3-phosphate synthase catalyses the sixth step of the shikimate pathway that is responsible for synthesizing aromatic compounds and is absent in mammals, which makes it a potential target for drugs development against microbial diseases. Here, we report the phosphate binding effects at the structure of the 5-enolpyruvylshikimate-3-phosphate synthase from Mycobacterium ...

2009
GRAHAM M. GIBB

Inorganic phosphate must be transported continuously into the mitochondrial matrix to maintain the steady-state oxidative phosphorylation of ADP. Specific uptake of this anion occurs via at least two distinct transport systems: an electroneutral inorganic phosphate-dicarboxylic acid exchange carrier and an inorganic phosphate-hydroxyl antiporter which catalyses the influx of about 90% of the mi...

Journal: :American Journal of Agricultural and Biological Sciences 2007

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