Background & Objective: Interleukin (IL)-10 is an important anti-inflammatory and immunomodulatory cytokine. Some authors believe that single nucleotide polymorphisms (SNP) in the promoter region of the IL-10 gene have been associated with susceptibility to HIV infection and progression to AIDS, but its role is not clearly defined yet. The present study was undertaken to evaluate the a...

The focus on online teaching and teachers’ digital competence (DC) has reached a new level following the emergence of COVID-19 its dramatic influence educational industry, requiring teachers to be equipped with DC. However, there is no consensus measuring framework Therefore, this study aimed construct reliable self-evaluation for in-service DC during teaching. data 1342 experience were obtaine...

κ-casein is a glycosilated protein belonging to a family of phosphoproteins (αs1,β, αs2,κ) that represents the major protein component in mammalian milk. κ-casein plays an essential role in the case of micelle stabilization, determining the size and the specific biological function. In the present study, we report the characterization of the partial sequence of κ-casein promoter region in the I...

κ-casein is a glycosilated protein belonging to a family of phosphoproteins (αs1,β, αs2,κ) that represents the major protein component in mammalian milk. κ-casein plays an essential role in the case of micelle stabilization, determining the size and the specific biological function. In the present study, we report the characterization of the partial sequence of κ-casein promoter region in the I...

Nagomi Kaigo Gakkou merupakan salah satu LPK yang mengirimkan pemagang caregiver terbanyak ke Jepang. Calon akan diberangkatkan Jepang harus mengikuti pelatihan pembelajaran bahasa dan kemampuan selama 9 hingga 12 bulan. Kemampuan calon diharapkan adalah pada tataran penguasaan bunpou (tata bahasa), goi (kosakata), choukai (menyimak), kaiwa (bercakap) Bahasa berada level setara N4. Berdasarkan ...

In this Letter, we make an attempt to estimate the masses of black holes and their distributions in BL Lac objects. We show the mass of black hole MBH ∝ ν −13/12 pk L 3/8 pk , where νpk and Lpk are the peak frequency and luminosity in the first bump of continuum, respectively. We find there are two populations of black hole masses in BL Lacs: the first has a lower-mass peak centred at ∼ 7.0× 10...

A self-regulated high-copy number plasmid containing chloramphenicol resistant gene, for the production of recombinant proteins under the regulation of bacteriophage ?pL promoter, was constructed. The designed 5024 base pair expression plasmid contained a heat sensitive repressor cI857 coding gene to regulate the function of ?pL promoter under heat shock induction. Using the constructed vector,...

In the human genome, chromosome 11 contains a cluster of matrix metalloproteinase (MMP) genes. Single nucleotide polymorphisms in the promoter region of MMP genes are important for MMP expression. A common adenine deletion polymorphism (5A) at position -1171 of the MMP-3 gene promoter (5´-AAAAAACCAT-3´ change to 5´-AAAAACCAT-3´) facilitates transcriptional factor binding and MMP-3 promoter acti...

Background The pro-inflammatory cytokine, tumor necrosis factor-alpha (TNF-α), is a pathogenic element for a number of disorders. Previous studies have reported that the -1031 T/C and -238 G/A polymorphisms in the promoter region of the TNF-α gene are important factors in reproductive-related disorders. One of the most common gynecological diseases of women during the reproductive years is endo...