Cytotoxic analogue of luteinizing hormone releasing hormone (LHRH), AN-207, binds with high affinity to LHRH receptors and can be targeted to tumors expressing these receptors. We investigated the expression of LHRH receptors in surgical specimens of human malignant melanoma and evaluated the effects of AN-207 in models of human melanoma. Human melanoma specimens derived from primary tumors or ...

Background & Objective:  Molybdenum trioxide nanoparticles (MoO3 NPs) have widespread applications in industries. However, the toxic and non-toxic effects of MoO3 NPs have not been fully investigated yet. In this study, effects of MoO3 NPs on ovary function of female rats were studied.  Materials & Methods:  In this study, 21 female rats were randomly divided into three groups (n=7): the first...

The presumptive diagnosis of constitutional delayed adolescence is difficult to substantiate. Clinical examination and routine biochemical testing are not sufficient to exclude isolated gonadotrophin deficiency. Seven males are reported who presented with delayed puberty. These patients were given 100 [±g luteinizing hormone-releasing hormone (LH-RH) intravenously, and the luteinizing hormone (...

The International Council for Standardization in Haematology (ICSH) in conjunction with Eurotrol, B.V. has released a new lot of the haemiglobincyanide or haemoglobin standard. This technical report describes the purpose, methodology in manufacturing, summary of value assignment data and availability of this standard material used for the standardization and calibration of whole blood haemoglob...

Aims and Objectives: This study aimed to assess compare follicle-stimulating hormone (FSH), luteinizing (LH), prolactin, thyroid-stimulating (TSH) levels in normal fertile females, patients with primary infertility, early pregnancy loss (EPL). Methods: Patients were divided into three groups of 25 each. Group I consisted II EPL, C females acted as the control group. Hormone different compared s...

Normal insulin with undetectable C-peptide concentrations indicates exogenous insulin administration in a bodybuilder (1 ). Insulin has anabolic functions that inhibit breakdown and promote nutrient storage (2 ). Pharmaceutical-grade insulin is available without prescription, providing an easy-to-obtain performance enhancer (3). Although a urinary testosterone/ luteinizing hormone ratio 30 is a...

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