background: new blood vessels formation is a critical step in tumor progression. vascular density affects the clinical outcome and prognosis of malignant tumors. the aim of this study was to investigate the relation between the vascular endothelial growth factor (vegf) expression and vascular density with the clinical and histopathologic features in oral squamous cell carcinoma (oscc).   method...

discoidin domain receptor (ddr) is a new member of the receptor tyrosine kinase family. there are two isoforms of discoidin domain receptor (ddr), ddr1 and ddr2. these receptors play a major role in the adhesion, motility and cell proliferation. due to the important role of ddr2 in the development of tumor extension, this receptor is pivotal in the field of carcinogenesis. the aim of this study...

Surgical treatment for mediastinal lymph node involvement in non-small cell lung cancer (NSCLC) will not have positive impact on survival. The present study aimed at investigating the role of positron emission tomography/computerized tomography (PET/CT) in staging NSCLC. Ninety-nine patients with maximal standard mediastinal lymph node involvement value (SUVmax) of 2.5 or more on PET/CT scannin...

BACKGROUND The incidence of the esophagogastric junction cancer is growing rapidly. The purpose of this study is to clarify the outcome of the ratio between metastatic and examined lymph nodes in esophagogastric junction cancer patients with or without 7 examined lymph nodes. METHODS A total of 3,481 patients who underwent operation are identified from the Surveillance, Epidemiology, and End ...

Oesophageal cancer is endemic in some regions of the Islamic Republic of Iran and efforts have made to find factors that play a role in its prognosis. We retrospectively examined the correlation of serum alkaline phosphatase (ALP) levels with several clinicopathological characteristics of 207 cases of oesophageal carcinoma. The mean ALP level in patients with lymph node involvement was signific...

TOPIC: Lung Pathology TYPE: Fellow Case Reports INTRODUCTION: Histiocytosis is a disorder when collection of hematopoietic-derived cells multiply without regulation but not considered malignant. The most recent classification was laid out by the World Health Organization in 2016 dividing them into multiple groups. Rosai-Dorfman disease typifies R group and unique its presentation ranging from s...