Relevance: Immunophenotyping with multiparameter flow cytofluorimetry differentiates classical variants of chronic B-lymphoproliferative diseases. However, some atypical conditions are hard to interpret, leading the search for new differential markers.
 The study aimed analyze predictive value monoclonal markers CD200, CD103, and CD11c in diagnostics hairy
 cell leukemia, splenic marg...

autoimmune lymphoproliferative syndrome is a disorder of lymphoid system regulation characterized by chronic splenomegaly, lymphadenopathy and autoimmune phenomena especially immune-mediated cytopenias. the hallmark of the disease is the presence in peripheral blood and lymphoid tissue of increased numbers of a normally rare t lymphocyte subset, usually referred to as “double-negative” t cells....