Congenital Hypothyroidism (CH) is a common preventable cause of mental retardation. The incidence CH 1 in 2500 to 3000 newborns. Most causes are thyroid dysgenesis and dyshormonogenesis. Some disorder like maternal autoantibodies, intake anti medication, iodine deficiency or excess can result transient CH. Common symptoms include decreased activity increased sleep, feeding difficulty, constipat...

Critically ill patients admitted into the intensive care units are susceptible to a wide array of complications that can be life-threatening, or lead long-term complications. Some inherent patient’s condition and others related therapeutics procedure. The prolonged prone positioning mechanical ventilation devices first risk factors for orofacial We report case 47-year-old male patient, with his...

Background Chronic kidney disease (CKD)-associated mucocutaneous manifestations significantly impair the quality of life but often remain understudied. They may also vary across regions, socioeconomic and nutritional status, and racial differences. Objectives To study the patterns of mucocutaneous disorders and their prevalence in CKD patients irrespective of clinical stage or dialysis status...

Introduction: Patients with Down syndrome (DS due to relative macroglossia and dynamic airway collapse) are vulnerable significant upper complications. Obstructive sleep apnea (OSA) is a common condition noted in about 79% of these children . Children OSA, or without DS, sensitive respiratory depression by drugs such as sedatives, opioids hypnotics. Abnormalities the cardiovascular system also ...

Morquio syndrome, also described as Mucopolysaccharidoses (MPS) type IV A in literature, are rare progressive and autosomal recessive lysosomal storage diseases characterised by deficiency of enzymes N- acetyl-galactosamine-6-sulphate sulphatase beta-galactosidase that decreases the catabolism glycosaminoglycans (GAGs) cause accumulation soft tissue, bone cartilage giving rise to severe skeletal...